Professeur des Universités
Neuropsychologie

Faculté : Univ Lille Nord de France – Université de Lille 3
Département : Unité de Formation et Recherche en Psychologie
Laboratoire : PSITEC – EA 4072
Membre de l’Axe de Recherche Neuropsychologie : Audition, Cognition, Action
Adresse postale :

Université Lille 3
Domaine Universitaire du Pont de Bois
BP 60149
59653 Villeneuve d’Ascq Cedex

Bureau : A5.327

♦ Thèmes de TE et TER | 2017-18 ♦

Contact par mail : christine.moroni@univ-lille3.fr

Thèmes de TE – Etudiants en 3^ième année de Licence

1) Evaluer des capacités d’inhibition et de flexibilité mentale :

Evaluer les capacités d’inhibition et de flexibilité mentale peut se révéler difficile chez des patients qui ont été peu scolarisés ou qui ne maîtrisent pas correctement le français. Le Five Digit Test (FDT) permet cette évaluation, toutefois il n’existe pas de normes contrôles pour la population française.

L’objectif de ce travail d’études pour l’année 2017-18 sera de compléter le recueil de données contrôles pour cette épreuve neuropsychologique et cela auprès d’une population tout venant (francophone ou non, scolarisée ou non….) dans le but de permettre la normalisation de cet outil et ainsi permettre son utilisation en pratique clinique.

Thème proposé à 2 étudiants

2) SEP et Vieillissement :

Les progrès de la prise en charge médicale des patients présentant une Sclérose en Plaques (SEP) ont permis à ces patients d’avancer en âge. Toutefois, les tests évaluant leurs capacités cognitives sont généralement normés pour une population jeune.

L’objectif de ce travail d’études pour l’année 2017-18 sera de compléter le recueil de données contrôles à une batterie cognitive pour des personnes âgées de 50 à 75 ans dans le but d’établir une normalisation pour cette batterie et de pouvoir ainsi permettre son utilisation en pratique clinique auprès de patients souffrant d’une SEP.

Thème proposé à 2 étudiants

3) Evaluation des capacités de mémoire de travail :

Depuis cinq ans, en collaboration avec Yves Martin (Neuropsychologue, Centre l’Espoir), nous avons développé une version informatisée du paradigme de Brown Peterson. Ce paradigme permet d’évaluer les capacités de mémoire de travail des patients cérébrolésés.

Pour cette année universitaire (2017-18), il est nécessaire de poursuivre le travail de normalisation de cette épreuve. Les performances de 193 participants contrôles ont déjà été acquises. Il est à présent nécessaire de confirmer les premiers résultats obtenus dans le but de créer un outil clinique pouvant être utilisé en pratique clinique. Pour cela, il sera demandé de poursuivre le recueil de données auprès de participants contrôles. Ce thème de recherche est associé à un stage recherche de 60 heures au centre L’Espoir.

Thème proposé à 2 étudiants
Thèmes de TER – Etudiants en 1^ière année de Master

1) Intérêt des corrélations anatomo-cliniques chez les patients présentant une pathologie dégénérative :

La prise en charge des patients adressés en consultation mémoire se compose de plusieurs examens dont le bilan neuropsychologique et l’imagerie médicale. Il est proposé pour ce thème de mémoire d’établir des corrélations anatomo-clinique entre les performances obtenues au bilan neuropsychologique et à la scintigraphie cérébrale pour une cohorte de 30 patients adressés en consultation mémoire. L’objectif sera d’établir des corrélations entre des hypo-débits sanguins cérébraux et des performances déficitaires aux épreuves neuropsychologiques.

Thème proposé à 2 étudiants

2) Répartition des capacités d’attention visuelle en cas d’atteinte du champ visuel :

Les relations entre les capacités d’attention visuelle et le champ visuel nécessitent d’être mieux définies dans le but de pouvoir développer des procédures de remédiation chez les patients cérébrolésés. L’appréhension des relations attention visuelle – champ visuel sera menée à l’aide de deux études utilisant des dispositifs expérimentaux différents.

La première étude utilisant le dispositif : UFOV a été proposé à 140 participants présentant une atteinte du champ visuel avec ou sans trouble cognitif, le but de l’étude sera de définir des profils de performances attentionnels spécifiques ou non à chaque atteinte du champ visuel.

La seconde étude utilise l’épreuve du Test des Cloches, classiquement employé à la recherche d’une négligence visuelle. Il est dans le cadre de cette étude proposée d’élaborer une nouvelle procédure d’analyse des données se basant sur une démarche dynamique de la réalisation de cette épreuve. Les données de patients cérébrolésés et de sujets contrôles seront utilisées pour définir au mieux cette procédure d’analyse des données.

Thème proposé à 3 étudiants

3) Mémoire sémantique : Intérêt d’une procédure rapide d’évaluation.

Il existe encore peu de procédure rapide pour évaluer la mémoire sémantique. Depuis quelques années, nous avons développé un test rapide : DemensIA et recueilli des données après de sujets contrôles et de patients adressés en consultation mémoire. L’objectif de ce mémoire est de conduire les analyses des données recueillies pour permettre de déterminer si cet outil est valide et si alors établir des normes et/ou des profils contrôles.

Thème proposé à 2 étudiants

♦ Encadrement de thèse ♦

Guilbert Alma (2013-2016) : Prise en charge non-médicamenteuse des troubles attentionnels des patients cérébrolésés : apport de la pratique musicale

Nizzi Marie-Christine (2013-) : Le soi vécu en première et en troisième personne par les patients et leur entourage dans plusieurs types de démences neuro-dégénératives

MANOLI Romina (2016 -) : Évaluation des facteurs cognitifs et psychologiques prédictifs du retour en formation de patients cérébrolésés

♦ liens utiles en relation avec la neuropsychologie ♦

♦ Matériel de test ♦

1) Adaptation française du Stroop Victoria – f SV : Manuel et Fichier de correction en lien avec les articles suivants :

Moroni, C. & Bayard, S. (2009). Processus d’inhibition : Quelle est leur évolution après 50 ans ? Psychologie et Neuropsychiatrie du vieillissement, 2, 121-9.

Bayard, S., Erkes, J., Moroni,C. & les Membres du Collège des Psychologues spécialisés en Neuropsychologie du Languedoc-Roussillon (2011). Victoria Stroop Test: Normative data in a sample group of older people and the study of their clinical applications in the assessment of inhibition in Alzheimer’s disease. Archives of Neuropsychology, 26(7), 653-61.

2) Evaluation des praxies gestuelles : Feuille réponse et gestes sans signification en lien avec l’article suivant :

Mahieux, F., Fabre, C., Galbrun, E., Dubrulle, A. & Moroni, C. et le groupe de réflexion sur les praxies du CMRR Ile de France-Sud (2009). Validation d’une batterie brève d’évaluation des praxies gestuelles pour Consultation Mémoire. Evaluation chez 419 témoins, 127 MCI et 320 patients souffrant d’une démence. Revue Neurologique, 165, 560-67.

3) Test des Faux Pas : Consignes, Test version patient, Test support psychologue, Cotation, Données contrôles en lien avec la communication suivante :

Delbeuck, X. Boutantin, J., Leroy, A., Pollet, M., Lebert, F., Pasquier, F., & Moroni, C. (2011). Utilité clinique du test des Faux Pas pour le diagnostic de démence fronto-temporale. Intervention dans le cadre des Journées d’Hiver de la Société de Neuropsychologie de Langue Française, Paris, 2 décembre 2011 [communication écrite].

4) Fluence d’action : Consignes et Fichier de correction (automatic calculation file) en lien avec l’article suivant :

Delbeuck, X., Debachy, B., Pasquier, F. & Moroni, C. (2013). Action and noun fluence testing to distinguish between Alzheimer’s disease and dementia with Lewy bodies. Journal of Clinical and Experimental Neuropsychology. DOI:10.1080/13803395.2013.763907

5) Test d’écoute dichotique (TED) : Matériel et feuille de réponse

6) Version Française du Hayling Test : Manuel et Fichier de correction en lien avec les articles suivant :

Bayard, S., Gély-Nargeot M-C, Raffard, S., Guerdoux-Ninot, E., Kamara, E., Gros-Balthazard, F., Jacus J-P & Moroni C., The Collège des Psychologues Cliniciens spécialisés en Neuropsychologie du Languedoc Roussillon (CPCN-Languedoc Roussillon) (accepted).French version of the Hayling Sentence Completion Test, Part I : Normative date and guidelines for error scoring. Archives of Neuropsychology.

Bayard,S., Moroni, C., Gély-Nargeot, M-C, Rossignol-Arifi,A., Kamara, E. & RaffardS. (Accepted). French version of the Hayling Sentence Clompletion Test, Part II : Clinical utility in schizophrenia and Parkinson’s disease. Archives of Neuropsychology

♦ Publication ♦

Description :
L’évaluation neuropsychologique repose sur un ensemble de connaissances théoriques couplé à une méthodologie spécifique. Cet ouvrage rappelle les principes méthodologiques fondamentaux de la démarche du bilan neuropsychologique à visée diagnostique et propose un ensemble de 20 cas cliniques permettant aux futurs professionnels de se familiariser avec les savoirs-faire du psychologue spécialisé en neuropsychologie. D’où l’intérêt de cet ouvrage, véritable guide pratique qui fournit des illustrations concrètes avec des cas cliniques dans différents domaines d’application de la neuropsychologie.

Les Auteurs :
Christine MORONI : Professeur en neuropsychologie à l’Université Lille 3, elle est aussi psychologue spécialisée en neuropsychologie au au CHRU Salengro à Lille
Pauline NARME : Maître de conférences en neuropsychologie à l’Université Paris-Descartes

Editeur : Dunod (11 mai 2016)
Collection : Psycho Sup
Langue : Français
ISBN-10: 2100740237
ISBN-13: 978-2100740239

♦ Publications ♦

56 Entrées « ‹ 1 de 2 › »

2018
1.	Manoli, Romina; Chartaux-Danjou, Laurence; Delecroix, Hélène; Daveluy, Walter; Moroni, Christine Intérêt de l’évaluation des capacités de consolidation à long terme des patients avec un traumatisme crânien grave 5500 - 5599 Conférence Journée d'Hiver de la Société de Neuropsychologie de Langue Française (Prix de la meilleure communication orale), 2018. BibTeX @conference{Manoli2018f, title = {Intérêt de l’évaluation des capacités de consolidation à long terme des patients avec un traumatisme crânien grave}, author = {Romina Manoli and Laurence Chartaux-Danjou and Hélène Delecroix and Walter Daveluy and Christine Moroni}, year = {2018}, date = {2018-12-07}, booktitle = {Journée d'Hiver de la Société de Neuropsychologie de Langue Française (Prix de la meilleure communication orale)}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
2.	Manoli Romina; Chartaux-Danjou, Laurence; Delecroix Hélène; Daveluy Walter; Moroni Christine Why evaluate one-week-delayed verbal recall in patients with severe traumatic brain injury? Article de journal Dans: Brain Injury, 2018. Liens \| BibTeX @article{Manoli2018e, title = {Why evaluate one-week-delayed verbal recall in patients with severe traumatic brain injury?}, author = {Manoli, Romina; Chartaux-Danjou, Laurence; Delecroix, Hélène; Daveluy, Walter; Moroni, Christine}, doi = {10.1080/02699052.2018.1539245}, year = {2018}, date = {2018-10-25}, journal = {Brain Injury}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer doi:10.1080/02699052.2018.1539245 Fermer
3.	Manoli Romina; Chartaux-Danjou, Laurence; Delecroix Helene; Daveluy Walter; Torre Fabien; Moroni Christine How can we anticipate failure in resuming vocational training following brain injury? A retrospective study 5500 - 5599 Conférence 12th International Society of Physical and Rehabilitation Medicine World Congress, Paris (France), e-poster , 2018. BibTeX @conference{Manoli2018d, title = {How can we anticipate failure in resuming vocational training following brain injury? A retrospective study}, author = {Manoli, Romina; Chartaux-Danjou, Laurence; Delecroix, Helene; Daveluy, Walter; Torre, Fabien; Moroni, Christine }, year = {2018}, date = {2018-07-08}, booktitle = {12th International Society of Physical and Rehabilitation Medicine World Congress, Paris (France)}, volume = {e-poster}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
4.	Manoli Romina; Chartaux-Danjou, Laurence; Delecroix Hélène; Daveluy Walter; Torre Fabien; Moroni Christine What Cognitive Factors Would Predict The Return To Vocational Training In Adults With Brain Injury? 5500 - 5599 Conférence 29th International Congress of Applied Psychology, Montréal (Canada), Oral communication , 2018. BibTeX @conference{Manoli2018b, title = {What Cognitive Factors Would Predict The Return To Vocational Training In Adults With Brain Injury?}, author = {Manoli, Romina; Chartaux-Danjou, Laurence; Delecroix, Hélène; Daveluy, Walter; Torre, Fabien; Moroni, Christine}, year = {2018}, date = {2018-06-26}, booktitle = {29th International Congress of Applied Psychology, Montréal (Canada)}, volume = {Oral communication}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
5.	Manoli Romina; Chartaux-Danjou, Laurence; Daveluy Walter; Delecroix Hélène; Noulhiane Marion; Moroni Christine New measures for long-term verbal memory consolidation assessment 5500 - 5599 Conférence 29th International Congress of Applied Psychology, Montréal (Canada), Oral communication , 2018. BibTeX @conference{Manoli2018c, title = {New measures for long-term verbal memory consolidation assessment}, author = {Manoli, Romina; Chartaux-Danjou, Laurence; Daveluy, Walter; Delecroix, Hélène; Noulhiane, Marion; Moroni, Christine}, year = {2018}, date = {2018-06-26}, booktitle = {29th International Congress of Applied Psychology, Montréal (Canada)}, volume = {Oral communication}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
6.	Manoli Romina; Chartaux-Danjou, Laurence; Delecroix Hélène; Daveluy Walter; Torre Fabien; Moroni Christine Predicting vocational outcome following brain injury: towards a better professional guidance 5500 - 5599 Conférence The 42nd Brain Injury Rehabilitation Conference, Williamsburg (Virginia, USA), Oral communication , 2018. BibTeX @conference{Manoli2018, title = {Predicting vocational outcome following brain injury: towards a better professional guidance}, author = {Manoli, Romina; Chartaux-Danjou, Laurence; Delecroix, Hélène; Daveluy, Walter; Torre, Fabien; Moroni, Christine}, year = {2018}, date = {2018-05-04}, booktitle = {The 42nd Brain Injury Rehabilitation Conference, Williamsburg (Virginia, USA)}, volume = {Oral communication}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
7.	Manoli, Romina; Chartaux-Danjou, Laurence; Mecheri, Halima; Delecroix, Hélène; Noulhiane, Marion; Moroni, Christine Extension to one week of verbal memory consolidation assessment Article de journal Dans: Neuropsychology, 32 (3), p. 366-373, 2018. Liens \| BibTeX @article{Manoli2017, title = {Extension to one week of verbal memory consolidation assessment}, author = {Romina Manoli and Laurence Chartaux-Danjou and Halima Mecheri and Hélène Delecroix and Marion Noulhiane and Christine Moroni}, doi = {10.1037/neu0000403}, year = {2018}, date = {2018-03-01}, journal = {Neuropsychology}, volume = {32}, number = {3}, pages = {366-373}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer doi:10.1037/neu0000403 Fermer
2017
8.	Manoli, Romina; Chartaux-Danjou, Laurence; Delecroix, Hélène; Daveluy, Walter; Moroni, Christine Long-term forgetting and memory impairment in patients with traumatic brain injury Workshop Cognitive neuroscience of memory: The Recollection, familiarity and novelty detection, University of Liege (Belgium), Poster , 2017. BibTeX @workshop{Manoli2017b, title = {Long-term forgetting and memory impairment in patients with traumatic brain injury}, author = {Romina Manoli and Laurence Chartaux-Danjou and Hélène Delecroix and Walter Daveluy and Christine Moroni}, year = {2017}, date = {2017-03-24}, booktitle = {Cognitive neuroscience of memory: The Recollection, familiarity and novelty detection, University of Liege (Belgium)}, volume = {Poster}, keywords = {}, pubstate = {published}, tppubtype = {workshop} } Fermer
9.	Bayard, Sophie; Moroni, Christine; Gély-Nargeot, Marie-Christine; Arifi, Alexia Rossignol-; Kamara, Emmanuelle; Raffard, Stéphane French Version of the Hayling Sentence Completion Test, Part II: Clinical Utility in Schizophrenia and Parkinson's Disease Article de journal Dans: Archives of Clinical Neuropsychology, p. 1–6, 2017, ISSN: 0887-6177, 1873-5843. Liens \| BibTeX @article{bayard_french_2017-1, title = {French Version of the Hayling Sentence Completion Test, Part II: Clinical Utility in Schizophrenia and Parkinson's Disease}, author = {Sophie Bayard and Christine Moroni and Marie-Christine Gély-Nargeot and Alexia Rossignol- Arifi and Emmanuelle Kamara and Stéphane Raffard}, url = {https://academic.oup.com/acn/acn/article/2975331/French}, doi = {10.1093/arclin/acx011}, issn = {0887-6177, 1873-5843}, year = {2017}, date = {2017-02-01}, urldate = {2017-08-28}, journal = {Archives of Clinical Neuropsychology}, pages = {1--6}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer https://academic.oup.com/acn/acn/article/2975331/French doi:10.1093/arclin/acx011 Fermer
10.	Guilbert, Alma; Clément, Sylvain; Moroni, Christine A rehabilitation program based on music practice for patients with unilateral spatial neglect: a single-case study Article de journal Dans: Neurocase, 23 (1), p. 12–21, 2017, ISSN: 1355-4794. Liens \| BibTeX @article{guilbert_rehabilitation_2017, title = {A rehabilitation program based on music practice for patients with unilateral spatial neglect: a single-case study}, author = {Alma Guilbert and Sylvain Clément and Christine Moroni}, doi = {10.1080/13554794.2016.1265652}, issn = {1355-4794}, year = {2017}, date = {2017-01-01}, journal = {Neurocase}, volume = {23}, number = {1}, pages = {12--21}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer doi:10.1080/13554794.2016.1265652 Fermer
11.	Bayard, Sophie; Gély-Nargeot, Marie-Christine; Raffard, Stéphane; Guerdoux-Ninot, Estelle; Kamara, Emmanuelle; Gros-Balthazard, Florent; Jacus, Jean-Pierre; Moroni, Christine French Version of the Hayling Sentence Completion Test, Part I: Normative Data and Guidelines for Error Scoring Article de journal Dans: Archives of Clinical Neuropsychology, p. 1–7, 2017, ISSN: 0887-6177, 1873-5843. Liens \| BibTeX @article{bayard_french_2017, title = {French Version of the Hayling Sentence Completion Test, Part I: Normative Data and Guidelines for Error Scoring}, author = {Sophie Bayard and Marie-Christine Gély-Nargeot and Stéphane Raffard and Estelle Guerdoux-Ninot and Emmanuelle Kamara and Florent Gros-Balthazard and Jean-Pierre Jacus and Christine Moroni}, url = {https://academic.oup.com/acn/acn/article/2972111/French}, doi = {10.1093/arclin/acx010}, issn = {0887-6177, 1873-5843}, year = {2017}, date = {2017-01-01}, urldate = {2017-08-28}, journal = {Archives of Clinical Neuropsychology}, pages = {1--7}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer https://academic.oup.com/acn/acn/article/2972111/French doi:10.1093/arclin/acx010 Fermer
2016
12.	Moroni, Christine; Narme, Pauline 20 cas cliniques en Neuropsychologie. Livre 2016, (Enfant, adulte, personne âgée). Résumé \| Liens \| BibTeX @book{Moroni2016, title = {20 cas cliniques en Neuropsychologie. }, author = {Christine Moroni and Pauline Narme }, editor = {Dunod}, url = {https://www.dunod.com/sciences-humaines-et-sociales/20-cas-cliniques-en-neuropsychologie-enfant-adulte-personne-agee}, year = {2016}, date = {2016-05-11}, abstract = {L’évaluation neuropsychologique repose sur un ensemble de connaissances théoriques couplé à une méthodologie spécifique. Cet ouvrage rappelle les principes méthodologiques fondamentaux de la démarche du bilan neuropsychologique à visée...}, note = {Enfant, adulte, personne âgée}, keywords = {}, pubstate = {published}, tppubtype = {book} } Fermer L’évaluation neuropsychologique repose sur un ensemble de connaissances théoriques couplé à une méthodologie spécifique. Cet ouvrage rappelle les principes méthodologiques fondamentaux de la démarche du bilan neuropsychologique à visée... Fermer https://www.dunod.com/sciences-humaines-et-sociales/20-cas-cliniques-en-neuropsy[...] Fermer
13.	Guilbert, Alma; Guillaume, Cécile Evaluation d'une plainte mnésique non authentifiée par un bilan standard incollection Dans: Moroni, Christine ; Narme, Pauline (Ed.): 20 cas cliniques en Neuropsychologie , 2016. BibTeX @incollection{guilbert_evaluation_2016, title = {Evaluation d'une plainte mnésique non authentifiée par un bilan standard}, author = {Alma Guilbert and Cécile Guillaume}, editor = {Moroni, Christine and Narme, Pauline}, year = {2016}, date = {2016-05-01}, volume = {20 cas cliniques en Neuropsychologie}, keywords = {}, pubstate = {published}, tppubtype = {incollection} } Fermer
14.	Moroni, Christine Evaluation neuropsychologique en cas de troubles sensoriels incollection Dans: L'évaluation neuropsychologique de la norme à l'exception / sous la direction d'Hélène Amieva, Catherine Belin et Didier Maillet, p. 125–136, De Boeck- Supérieur, 2016, ISBN: 978-2-35327-352-2. Liens \| BibTeX @incollection{moroni_evaluation_2016, title = {Evaluation neuropsychologique en cas de troubles sensoriels}, author = {Christine Moroni}, url = {http://www.deboecksuperieur.com/ouvrage/9782353273522-levaluation-neuropsychologique}, isbn = {978-2-35327-352-2}, year = {2016}, date = {2016-05-01}, booktitle = {L'évaluation neuropsychologique de la norme à l'exception / sous la direction d'Hélène Amieva, Catherine Belin et Didier Maillet}, pages = {125--136}, publisher = {De Boeck- Supérieur}, edition = {1re édition}, series = {Neuropsychologie}, keywords = {}, pubstate = {published}, tppubtype = {incollection} } Fermer http://www.deboecksuperieur.com/ouvrage/9782353273522-levaluation-neuropsycholog[...] Fermer
15.	Moroni, Christine Transfert inter-hémisphérique et activité motrice involontaire (Alien Hand). incollection Dans: 20 cas cliniques en neuropsychologie / sous la direction de Christine Moroni, Pauline Narme, p. 119–133, Dunod, 2016, ISBN: 978-2-10-074023-9. BibTeX @incollection{moroni_transfert_2016, title = {Transfert inter-hémisphérique et activité motrice involontaire (Alien Hand).}, author = {Christine Moroni}, isbn = {978-2-10-074023-9}, year = {2016}, date = {2016-05-01}, booktitle = {20 cas cliniques en neuropsychologie / sous la direction de Christine Moroni, Pauline Narme}, pages = {119--133}, publisher = {Dunod}, series = {Psycho sup}, keywords = {}, pubstate = {published}, tppubtype = {incollection} } Fermer
16.	Guilbert, Alma; Clément, Sylvain; Moroni, Christine Musical practice as a way to rehabilitate unilateral spatial neglect: A single case study Inproceedings Dans: 2016. BibTeX @inproceedings{Guilbert2016, title = {Musical practice as a way to rehabilitate unilateral spatial neglect: A single case study}, author = {Alma Guilbert and Sylvain Clément and Christine Moroni}, year = {2016}, date = {2016-03-01}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Fermer
17.	Durand, Thomas; Léger, Isabelle; Bompaire, Flavie; Boone, Mathieu; Moroni, Christine; Delgadillo, Daniel; Dornier, Stéphanie; Psimaras, Dimitri; Noël, Georges; Taillia, Hervé; Ricard, Damien Tumeurs cérébrales : neurotoxicité des traitements et évaluations cognitives Article de journal Dans: Revue de neuropsychologie, 8 (3), p. 192–200, 2016, ISSN: 2101-6739. Résumé \| Liens \| BibTeX @article{durand_tumeurs_2016, title = {Tumeurs cérébrales : neurotoxicité des traitements et évaluations cognitives}, author = {Thomas Durand and Isabelle Léger and Flavie Bompaire and Mathieu Boone and Christine Moroni and Daniel Delgadillo and Stéphanie Dornier and Dimitri Psimaras and Georges Noël and Hervé Taillia and Damien Ricard}, url = {http://www.cairn.info/resume.php?ID_ARTICLE=RNE_083_0192}, doi = {doi:10.1684/nrp.2016.0392}, issn = {2101-6739}, year = {2016}, date = {2016-02-01}, urldate = {2017-02-27}, journal = {Revue de neuropsychologie}, volume = {8}, number = {3}, pages = {192--200}, abstract = {L’amélioration des traitements neuro-oncologiques ces dernières années permettant une survie plus longue des patients atteints de tumeurs cérébrales fait émerger la problématique des effets secondaires à long terme. Parmi ces effets secondaires, les troubles cognitifs sont au premier plan et impactent lourdement la qualité de vie des patients. Leur prise en compte constitue actuellement un challenge majeur en neuro-oncologie et nécessite un effort en recherche clinique ainsi que dans le suivi à moyen et à long terme des patients en pratique courante. Les troubles cognitifs peuvent être causés par la progression tumorale et/ou par la récidive tumorale, mais sont souvent provoqués par la neurotoxicité inhérente aux traitements. L’objectif de cet article est de présenter les troubles cognitifs induits par les traitements anti-tumoraux ainsi que par les traitements concomitants les plus courants en neuro-oncologie. Nous exposons ensuite les principaux biais auxquels se heurte l’évaluation neuropsychologique dans ce contexte et présentons la batterie cognitive proposée par le Grec-Onco, actuellement utilisée dans différents protocoles de recherche clinique.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer L’amélioration des traitements neuro-oncologiques ces dernières années permettant une survie plus longue des patients atteints de tumeurs cérébrales fait émerger la problématique des effets secondaires à long terme. Parmi ces effets secondaires, les troubles cognitifs sont au premier plan et impactent lourdement la qualité de vie des patients. Leur prise en compte constitue actuellement un challenge majeur en neuro-oncologie et nécessite un effort en recherche clinique ainsi que dans le suivi à moyen et à long terme des patients en pratique courante. Les troubles cognitifs peuvent être causés par la progression tumorale et/ou par la récidive tumorale, mais sont souvent provoqués par la neurotoxicité inhérente aux traitements. L’objectif de cet article est de présenter les troubles cognitifs induits par les traitements anti-tumoraux ainsi que par les traitements concomitants les plus courants en neuro-oncologie. Nous exposons ensuite les principaux biais auxquels se heurte l’évaluation neuropsychologique dans ce contexte et présentons la batterie cognitive proposée par le Grec-Onco, actuellement utilisée dans différents protocoles de recherche clinique. Fermer http://www.cairn.info/resume.php?ID_ARTICLE=RNE_083_0192 doi:doi:10.1684/nrp.2016.0392 Fermer
18.	Guilbert, Alma; Clément, Sylvain; Martin, Yves; Feuillet, Alexia; Moroni, Christine Exogenous orienting of attention in hearing: a virtual reality paradigm to assess auditory attention in neglect patients Article de journal Dans: Exp Brain Res, 234 (10), p. 2893–2903, 2016, ISSN: 0014-4819, 1432-1106. Résumé \| Liens \| BibTeX @article{guilbert_exogenous_2016, title = {Exogenous orienting of attention in hearing: a virtual reality paradigm to assess auditory attention in neglect patients}, author = {Alma Guilbert and Sylvain Clément and Yves Martin and Alexia Feuillet and Christine Moroni}, url = {https://link.springer.com/article/10.1007/s00221-016-4691-8}, doi = {10.1007/s00221-016-4691-8}, issn = {0014-4819, 1432-1106}, year = {2016}, date = {2016-01-01}, urldate = {2017-02-27}, journal = {Exp Brain Res}, volume = {234}, number = {10}, pages = {2893--2903}, abstract = {While mechanisms of orienting attention in unilateral spatial neglect (USN) have frequently been studied in the visual domain, these mechanisms remain relatively unexplored in the auditory domain. Our first goal was to replicate Spence and Driver’s (J Exp Psychol Hum 22:1005–1030, 1994) results with a virtual reality paradigm. This paradigm simulated a 3-dimensional auditory space with headphones. Our second aim was to study auditory profiles of orienting attention in USN. In a first experiment, 18 healthy participants performed an auditory cueing spatial paradigm (either a target-detection task or a target-lateralization task). In a second experiment, 14 right-stroke patients (10 with USN and 4 without USN) performed these two same tasks. As in Spence and Driver’s (J Exp Psychol Hum 22:1005–1030, 1994), our first experiment showed that spatial representations are not utilized for the detection of auditory stimuli. However, during the lateralization task, participants were quicker to detect targets preceded by a spatially congruent cue, which suggests that our paradigm could be suitable for studying orienting attention in hearing. Our second experiment found that patients with USN also needed an explicit spatial task to be sensitive to auditory spatial cueing. In the target-lateralization task, they showed effects lateralized only to one side of space, whereas patients without USN did not. Although our paradigm needs replications to better understand orienting attention impairments in hearing in USN, this study could have implications for the development of clinical tasks that could assess auditory spatial attention in USN syndrome.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer While mechanisms of orienting attention in unilateral spatial neglect (USN) have frequently been studied in the visual domain, these mechanisms remain relatively unexplored in the auditory domain. Our first goal was to replicate Spence and Driver’s (J Exp Psychol Hum 22:1005–1030, 1994) results with a virtual reality paradigm. This paradigm simulated a 3-dimensional auditory space with headphones. Our second aim was to study auditory profiles of orienting attention in USN. In a first experiment, 18 healthy participants performed an auditory cueing spatial paradigm (either a target-detection task or a target-lateralization task). In a second experiment, 14 right-stroke patients (10 with USN and 4 without USN) performed these two same tasks. As in Spence and Driver’s (J Exp Psychol Hum 22:1005–1030, 1994), our first experiment showed that spatial representations are not utilized for the detection of auditory stimuli. However, during the lateralization task, participants were quicker to detect targets preceded by a spatially congruent cue, which suggests that our paradigm could be suitable for studying orienting attention in hearing. Our second experiment found that patients with USN also needed an explicit spatial task to be sensitive to auditory spatial cueing. In the target-lateralization task, they showed effects lateralized only to one side of space, whereas patients without USN did not. Although our paradigm needs replications to better understand orienting attention impairments in hearing in USN, this study could have implications for the development of clinical tasks that could assess auditory spatial attention in USN syndrome. Fermer https://link.springer.com/article/10.1007/s00221-016-4691-8 doi:10.1007/s00221-016-4691-8 Fermer
19.	Guilbert, Alma; Clément, Sylvain; Senouci, Latifa; Pontzeele, Sylvain; Martin, Yves; Moroni, Christine Auditory lateralisation deficits in neglect patients Article de journal Dans: Neuropsychologia, 85 , p. 177–183, 2016, ISSN: 0028-3932. Résumé \| Liens \| BibTeX @article{guilbert_auditory_2016, title = {Auditory lateralisation deficits in neglect patients}, author = {Alma Guilbert and Sylvain Clément and Latifa Senouci and Sylvain Pontzeele and Yves Martin and Christine Moroni}, doi = {10.1016/j.neuropsychologia.2016.03.024}, issn = {0028-3932}, year = {2016}, date = {2016-01-01}, journal = {Neuropsychologia}, volume = {85}, pages = {177--183}, abstract = {Although visual deficits due to unilateral spatial neglect (USN) have been frequently described in the literature, fewer studies have been interested in directional hearing impairment in USN. The aim of this study was to explore sound lateralisation deficits in USN. Using a paradigm inspired by Tanaka et al. (1999), interaural time differences (ITD) were presented over headphones to give the illusion of a leftward or a rightward movement of sound. Participants were asked to respond “right” and “left” as soon as possible to indicate whether they heard the sound moving to the right or to the left side of the auditory space. We additionally adopted a single-case method to analyse the performance of 15 patients with right-hemisphere (RH) stroke and added two additional measures to underline sound lateralisation on the left side and on the right side. We included 15 patients with RH stoke (5 with a severe USN, 5 with a mild USN and 5 without USN) and 11 healthy age-matched participants. We expected to replicate findings of abnormal sound lateralisation in USN. However, although a sound lateralisation deficit was observed in USN, two different deficit profiles were identified. Namely, patients with a severe USN seemed to have left sound lateralisation impairment whereas patients with a mild USN seemed to be more influenced by a systematic bias in auditory representation with respect to body meridian axis (egocentric deviation). This latter profile was unexpected as sounds were manipulated with ITD and, thus, would not be perceived as coming from an external source of the head. Future studies should use this paradigm in order to better understand these two distinct profiles.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Although visual deficits due to unilateral spatial neglect (USN) have been frequently described in the literature, fewer studies have been interested in directional hearing impairment in USN. The aim of this study was to explore sound lateralisation deficits in USN. Using a paradigm inspired by Tanaka et al. (1999), interaural time differences (ITD) were presented over headphones to give the illusion of a leftward or a rightward movement of sound. Participants were asked to respond “right” and “left” as soon as possible to indicate whether they heard the sound moving to the right or to the left side of the auditory space. We additionally adopted a single-case method to analyse the performance of 15 patients with right-hemisphere (RH) stroke and added two additional measures to underline sound lateralisation on the left side and on the right side. We included 15 patients with RH stoke (5 with a severe USN, 5 with a mild USN and 5 without USN) and 11 healthy age-matched participants. We expected to replicate findings of abnormal sound lateralisation in USN. However, although a sound lateralisation deficit was observed in USN, two different deficit profiles were identified. Namely, patients with a severe USN seemed to have left sound lateralisation impairment whereas patients with a mild USN seemed to be more influenced by a systematic bias in auditory representation with respect to body meridian axis (egocentric deviation). This latter profile was unexpected as sounds were manipulated with ITD and, thus, would not be perceived as coming from an external source of the head. Future studies should use this paradigm in order to better understand these two distinct profiles. Fermer doi:10.1016/j.neuropsychologia.2016.03.024 Fermer
20.	Feuillet, Alexia; Moroni, Christine Evaluation des capacités cognitives d’un enfant adopté à l’étranger : Apport et intérêt de la neuropsychologie incollection Dans: 20 cas cliniques en neuropsychologie / sous la direction de Christine Moroni, Pauline Narme, p. 375–395, Dunod, 2016, ISBN: 978-2-10-074023-9. BibTeX @incollection{feuillet_evaluation_2016, title = {Evaluation des capacités cognitives d’un enfant adopté à l’étranger : Apport et intérêt de la neuropsychologie}, author = {Alexia Feuillet and Christine Moroni}, isbn = {978-2-10-074023-9}, year = {2016}, date = {2016-01-01}, booktitle = {20 cas cliniques en neuropsychologie / sous la direction de Christine Moroni, Pauline Narme}, pages = {375--395}, publisher = {Dunod}, series = {Psycho sup}, keywords = {}, pubstate = {published}, tppubtype = {incollection} } Fermer
21.	Guilbert, Alma; Clément, Sylvain; Moroni, Christine Évaluation de la latéralisation sonore dans la négligence spatiale unilatérale : cas de Mme B Article de journal Dans: Revue de neuropsychologie, 8 (2), p. 118–125, 2016, ISSN: 2101-6739. Liens \| BibTeX @article{guilbert_evaluation_2016-1, title = {Évaluation de la latéralisation sonore dans la négligence spatiale unilatérale : cas de Mme B}, author = {Alma Guilbert and Sylvain Clément and Christine Moroni}, url = {http://www.cairn.info/resume.php?ID_ARTICLE=RNE_082_0118}, issn = {2101-6739}, year = {2016}, date = {2016-01-01}, urldate = {2017-02-27}, journal = {Revue de neuropsychologie}, volume = {8}, number = {2}, pages = {118--125}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer http://www.cairn.info/resume.php?ID_ARTICLE=RNE_082_0118 Fermer
22.	Nizzi, Marie-Christine; Belin, Catherine; Maillet, Didier; Moroni, Christine Implication de plusieurs processus cognitifs dans le vécu identitaire des patients Alzheimer et rôle de l’âge subjectif comme marqueur identitaire Article de journal Dans: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement, 14 (3), p. 341–350, 2016, ISSN: 2115-8789. Liens \| BibTeX @article{nizzi_implication_2016, title = {Implication de plusieurs processus cognitifs dans le vécu identitaire des patients Alzheimer et rôle de l’âge subjectif comme marqueur identitaire}, author = {Marie-Christine Nizzi and Catherine Belin and Didier Maillet and Christine Moroni}, url = {http://www.jle.com/fr/revues/gpn/e-docs/implication_de_plusieurs_processus_cognitifs_dans_le_vecu_identitaire_des_patients_alzheimer_et_role_de_lage_subjectif_comme_marqueur_identitaire_308098/article.phtml?tab=texte}, doi = {10.1684/pnv.2016.0624}, issn = {2115-8789}, year = {2016}, date = {2016-01-01}, urldate = {2017-02-27}, journal = {Gériatrie et Psychologie Neuropsychiatrie du Vieillissement}, volume = {14}, number = {3}, pages = {341--350}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer http://www.jle.com/fr/revues/gpn/e-docs/implication_de_plusieurs_processus_cogni[...] doi:10.1684/pnv.2016.0624 Fermer
2015
23.	Guilbert, Alma; Clément, Sylvain; Moroni, Christine La pratique musicale comme outil de rééducation de la négligence spatiale unilatérale 5500 - 5599 Conférence 2015. BibTeX @conference{Guilbert2015, title = {La pratique musicale comme outil de rééducation de la négligence spatiale unilatérale}, author = {Alma Guilbert and Sylvain Clément and Christine Moroni}, year = {2015}, date = {2015-12-01}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
24.	Guilbert, Alma; Clément, Sylvain; Moroni, Christine Midpoint auditif: évaluation de la négligence spatiale unilatérale en modalité auditive. 5500 - 5599 Conférence 2015. BibTeX @conference{guilbert_midpoint_2015, title = {Midpoint auditif: évaluation de la négligence spatiale unilatérale en modalité auditive.}, author = {Alma Guilbert and Sylvain Clément and Christine Moroni}, year = {2015}, date = {2015-05-01}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
25.	Caroline, Marks; Ikram, Bouacha; Sabine, Defoort; Daniele, Basset; Christine, Moroni Principes de réalisation du champ visuel attentionnel et élaboration de normes Article de journal Dans: 38 (6), p. 486–492, 2015, ISSN: 0181-5512. Résumé \| Liens \| BibTeX @article{caroline_principes_2015, title = {Principes de réalisation du champ visuel attentionnel et élaboration de normes}, author = {Marks Caroline and Bouacha Ikram and Defoort Sabine and Basset Daniele and Moroni Christine}, url = {http://www.sciencedirect.com/science/article/pii/S0181551215001114}, doi = {10.1016/j.jfo.2014.11.014}, issn = {0181-5512}, year = {2015}, date = {2015-05-01}, urldate = {2016-05-03}, volume = {38}, number = {6}, pages = {486--492}, abstract = {RésuméIntroduction Le champ visuel attentionnel est un examen permettant de prendre en compte l’influence de facteurs attentionnels lors de l’évaluation du champ visuel. L’objectif de notre étude était de recueillir des données contrôles adaptées à notre procédure utilisée en pratique clinique, lors des consultations d’évaluation à la reprise de la conduite automobile. Patients et méthodes Cinquante-deux participants témoins âgés de 19 à 69 ans, sans antécédent ophtalmologique ou neurologique, ont réalisé notre adaptation de la procédure de champ visuel attentionnel. Le nombre d’omissions de cibles centrales et latérales et les temps de réponses ont été mesurés au cours de trois tâches attentionnelles. Résultats Le nombre moyen d’omissions et les temps moyens de détection des cibles augmentent progressivement au cours des trois tâches. L’âge et le sexe sont des facteurs influençant de manière significative les temps de détection des cibles, les hommes et les sujets jeunes (de 19 à 29 ans) étant plus rapides. Conclusion Le champ visuel attentionnel est reconnu comme un outil fiable dans le cadre de l’évaluation de la reprise de la conduite automobile. Pour permettre une utilisation adaptée à notre pratique clinique, il était indispensable d’élaborer des normes pour interpréter les performances attentionnelles des patients ayant une atteinte de leur champ visuel. SummaryPurpose The useful field of view is a test which takes into account the influence of patient attention during the evaluation of the visual field. This study aims to generate normative data for an adaptation of the useful field of view (UFOV) test. These normative data are essential to judge, in a clinical setting, whether patients’ performance is normal or not across demographically similar peers, in order to advise whether or not to resume driving after a brain injury (traumatic brain injury, stroke or cerebral tumour). Patients and methods This study examined demographic influences on an UFOV adaptation in a sample of 52 control participants (17 males and 35 females, aged 19 to 69) with no prior ophthalmologic or neurologic history. This adaptation used three visual attention tasks. In a simple task (ST), the participant had to detect, as fast as (s)he could, a single target in a visual display; in a double task (DT,) (s)he had to detect both a central and a lateral target in a double task with visual distractions present on the screen. The number of missed targets and the time needed to detect them are measured. Results Time to detect target was found to differ by gender and by age. Men and young people (from 19 to 29 years) are faster at detecting central and lateral targets. However, no demographic influence was observed on the number of missed targets. Conclusions A normative table for this French UFOV adaptation is provided. This will allow clinicians to compare patient performance with similar peers and may help in identifying persons who would benefit from training on a driving simulator or having a road test with a driving-school.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer RésuméIntroduction Le champ visuel attentionnel est un examen permettant de prendre en compte l’influence de facteurs attentionnels lors de l’évaluation du champ visuel. L’objectif de notre étude était de recueillir des données contrôles adaptées à notre procédure utilisée en pratique clinique, lors des consultations d’évaluation à la reprise de la conduite automobile. Patients et méthodes Cinquante-deux participants témoins âgés de 19 à 69 ans, sans antécédent ophtalmologique ou neurologique, ont réalisé notre adaptation de la procédure de champ visuel attentionnel. Le nombre d’omissions de cibles centrales et latérales et les temps de réponses ont été mesurés au cours de trois tâches attentionnelles. Résultats Le nombre moyen d’omissions et les temps moyens de détection des cibles augmentent progressivement au cours des trois tâches. L’âge et le sexe sont des facteurs influençant de manière significative les temps de détection des cibles, les hommes et les sujets jeunes (de 19 à 29 ans) étant plus rapides. Conclusion Le champ visuel attentionnel est reconnu comme un outil fiable dans le cadre de l’évaluation de la reprise de la conduite automobile. Pour permettre une utilisation adaptée à notre pratique clinique, il était indispensable d’élaborer des normes pour interpréter les performances attentionnelles des patients ayant une atteinte de leur champ visuel. SummaryPurpose The useful field of view is a test which takes into account the influence of patient attention during the evaluation of the visual field. This study aims to generate normative data for an adaptation of the useful field of view (UFOV) test. These normative data are essential to judge, in a clinical setting, whether patients’ performance is normal or not across demographically similar peers, in order to advise whether or not to resume driving after a brain injury (traumatic brain injury, stroke or cerebral tumour). Patients and methods This study examined demographic influences on an UFOV adaptation in a sample of 52 control participants (17 males and 35 females, aged 19 to 69) with no prior ophthalmologic or neurologic history. This adaptation used three visual attention tasks. In a simple task (ST), the participant had to detect, as fast as (s)he could, a single target in a visual display; in a double task (DT,) (s)he had to detect both a central and a lateral target in a double task with visual distractions present on the screen. The number of missed targets and the time needed to detect them are measured. Results Time to detect target was found to differ by gender and by age. Men and young people (from 19 to 29 years) are faster at detecting central and lateral targets. However, no demographic influence was observed on the number of missed targets. Conclusions A normative table for this French UFOV adaptation is provided. This will allow clinicians to compare patient performance with similar peers and may help in identifying persons who would benefit from training on a driving simulator or having a road test with a driving-school. Fermer http://www.sciencedirect.com/science/article/pii/S0181551215001114 doi:10.1016/j.jfo.2014.11.014 Fermer
26.	Defoort, Sabine; Basset, Daniele; Marks, Caroline; Bouacha, Ikram; Moroni, Christine Principes de réalisation du champ visuel attentionnel et élaboration de normes. Article de journal Dans: Journal Français d’Ophtalmologie, 38 , p. 486–492, 2015. Résumé \| Liens \| BibTeX @article{Defoort2015, title = {Principes de réalisation du champ visuel attentionnel et élaboration de normes.}, author = {Sabine Defoort and Daniele Basset and Caroline Marks and Ikram Bouacha and Christine Moroni}, doi = {j.jfo.2014.11.014}, year = {2015}, date = {2015-01-01}, journal = {Journal Français d’Ophtalmologie}, volume = {38}, pages = {486--492}, abstract = {Résumé Introduction. — Le champ visuel attentionnel est un examen permettant de prendre en compte l’influence de facteurs attentionnels lors de l’évaluation du champ visuel. L’objectif de notre étude était de recueillir des données contrôles adaptées à notre procédure utilisée en pratique clinique, lors des consultations d’évaluation à la reprise de la conduite automobile. Patients et méthodes. — Cinquante-deux participants témoins âgés de 19 à 69 ans, sans anté- cédent ophtalmologique ou neurologique, ont réalisé notre adaptation de la procédure de champ visuel attentionnel. Le nombre d’omissions de cibles centrales et latérales et les temps de réponses ont été mesurés au cours de trois tâches attentionnelles. Résultats. — Le nombre moyen d’omissions et les temps moyens de détection des cibles aug- mentent progressivement au cours des trois tâches. L’âge et le sexe sont des facteurs influen ̧cant de manière significative les temps de détection des cibles, les hommes et les sujets jeunes (de 19 à 29 ans) étant plus rapides. Conclusion. — Le champ visuel attentionnel est reconnu comme un outil fiable dans le cadre de l’évaluation de la reprise de la conduite automobile. Pour permettre une utilisation adaptée à notre pratique clinique, il était indispensable d’élaborer des normes pour interpréter les performances attentionnelles des patients ayant une atteinte de leur champ visuel. © 2015 Elsevier Masson SAS. Tous droits réservés.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Résumé Introduction. — Le champ visuel attentionnel est un examen permettant de prendre en compte l’influence de facteurs attentionnels lors de l’évaluation du champ visuel. L’objectif de notre étude était de recueillir des données contrôles adaptées à notre procédure utilisée en pratique clinique, lors des consultations d’évaluation à la reprise de la conduite automobile. Patients et méthodes. — Cinquante-deux participants témoins âgés de 19 à 69 ans, sans anté- cédent ophtalmologique ou neurologique, ont réalisé notre adaptation de la procédure de champ visuel attentionnel. Le nombre d’omissions de cibles centrales et latérales et les temps de réponses ont été mesurés au cours de trois tâches attentionnelles. Résultats. — Le nombre moyen d’omissions et les temps moyens de détection des cibles aug- mentent progressivement au cours des trois tâches. L’âge et le sexe sont des facteurs influen ̧cant de manière significative les temps de détection des cibles, les hommes et les sujets jeunes (de 19 à 29 ans) étant plus rapides. Conclusion. — Le champ visuel attentionnel est reconnu comme un outil fiable dans le cadre de l’évaluation de la reprise de la conduite automobile. Pour permettre une utilisation adaptée à notre pratique clinique, il était indispensable d’élaborer des normes pour interpréter les performances attentionnelles des patients ayant une atteinte de leur champ visuel. © 2015 Elsevier Masson SAS. Tous droits réservés. Fermer doi:j.jfo.2014.11.014 Fermer
27.	Taillia, Hervé; Léger, Isabelle; Christine, Moroni; Mathieu, Boone; C, Belin; Didier, Maillet; M, Lange La batterie du Grec-Onco (Groupe de Réflexion sur les Evaluations Cognitives en ONCOlogie). Gremoire 2, Tests et échelles des maladies neurologiques avec symptomatologie cognitive. incollection Dans: pp Sous la direction de Laurence Hugonot-Diener Catherine Thomas-Antérion et François Sellal. De Boeck-Solal. Paris, : 33-37 (Ed.): 2015. BibTeX @incollection{taillia_batterie_2015, title = {La batterie du Grec-Onco (Groupe de Réflexion sur les Evaluations Cognitives en ONCOlogie). Gremoire 2, Tests et échelles des maladies neurologiques avec symptomatologie cognitive.}, author = {Hervé Taillia and Isabelle Léger and Moroni Christine and Boone Mathieu and Belin C and Maillet Didier and Lange M}, editor = {Sous la direction de Laurence Hugonot-Diener, Catherine Thomas-Antérion et François Sellal. De Boeck-Solal. Paris, pp : 33-37.}, year = {2015}, date = {2015-01-01}, keywords = {}, pubstate = {published}, tppubtype = {incollection} } Fermer
2014
28.	Chartaux-Danjou, Laurence; Moroni, Christine; Delecroix, Hélène Quels impacts dans le travail pour quels troubles cognitifs ? Article de journal Dans: Archives des maladies professionnelles et de l’environnement, 5 (72), p. 530–531, 2014. Liens \| BibTeX @article{Chartaux-Danjou2014, title = {Quels impacts dans le travail pour quels troubles cognitifs ?}, author = {Laurence Chartaux-Danjou and Christine Moroni and Hélène Delecroix}, doi = {10.1016/j.admp.2014.07.041}, year = {2014}, date = {2014-11-01}, journal = {Archives des maladies professionnelles et de l’environnement}, volume = {5}, number = {72}, pages = {530--531}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer doi:10.1016/j.admp.2014.07.041 Fermer
29.	Leclercq, Eugénie; Cabaret, Maryline; Guilbert, Alma; Jougleux, Caroline; Vermersch, Patrick; Moroni, Christine The influence of age and illness duration on cognitive impairment in aging patients with relapsing-remitting multiple sclerosis (RR-MS). Article de journal Dans: Gériatrie et psychologie neuropsychiatrie du vieillissement, 12 (3), p. 331–8, 2014, ISSN: 2115-7863. Résumé \| Liens \| BibTeX @article{leclercq_[influence_2014, title = {The influence of age and illness duration on cognitive impairment in aging patients with relapsing-remitting multiple sclerosis (RR-MS).}, author = {Eugénie Leclercq and Maryline Cabaret and Alma Guilbert and Caroline Jougleux and Patrick Vermersch and Christine Moroni}, url = {http://www.ncbi.nlm.nih.gov/pubmed/25245320}, doi = {10.1684/pnv.2014.0482}, issn = {2115-7863}, year = {2014}, date = {2014-01-01}, journal = {Gériatrie et psychologie neuropsychiatrie du vieillissement}, volume = {12}, number = {3}, pages = {331--8}, abstract = {The aim of this study was to dissociate age and duration of illness effects on cognitive impairment of patients with relapsing-remitting multiple sclerosis. Cognitive impairment among patients with multiple sclerosis (MS) is well known. However, few studies were devoted to assess the respective role of disease duration and age on cognitive functions in MS patients. Therefore, two studies were carried out on relapsing-remitting MS (RR-MS) patients using some tests of the BCcogSEP–a French test battery evaluating cognitive functions in MS. The cognitive deficits of RR-MS patients aged 50 years and over and whose symptoms had been present for more than 20 years were more severe than those of MS patients with a shorter illness duration (less than 10 years) or matched-age control participants. The more impaired cognitive functions were information-processing speed, episodic memory, verbal fluency and attention. On the other hand, cognitive performances of young RR-MS patients were similar to those of older RR-MS patients when all patients had the same illness duration (8 years in this study). Older patients even achieved better performance than younger ones on verbal fluency. This can be partly explained by the theory of cognitive reserve, as reported in previous cognitive aging studies. In RR-MS patients, the influence of illness duration seems to be a predominant factor in the development of cognitive impairment.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer The aim of this study was to dissociate age and duration of illness effects on cognitive impairment of patients with relapsing-remitting multiple sclerosis. Cognitive impairment among patients with multiple sclerosis (MS) is well known. However, few studies were devoted to assess the respective role of disease duration and age on cognitive functions in MS patients. Therefore, two studies were carried out on relapsing-remitting MS (RR-MS) patients using some tests of the BCcogSEP–a French test battery evaluating cognitive functions in MS. The cognitive deficits of RR-MS patients aged 50 years and over and whose symptoms had been present for more than 20 years were more severe than those of MS patients with a shorter illness duration (less than 10 years) or matched-age control participants. The more impaired cognitive functions were information-processing speed, episodic memory, verbal fluency and attention. On the other hand, cognitive performances of young RR-MS patients were similar to those of older RR-MS patients when all patients had the same illness duration (8 years in this study). Older patients even achieved better performance than younger ones on verbal fluency. This can be partly explained by the theory of cognitive reserve, as reported in previous cognitive aging studies. In RR-MS patients, the influence of illness duration seems to be a predominant factor in the development of cognitive impairment. Fermer http://www.ncbi.nlm.nih.gov/pubmed/25245320 doi:10.1684/pnv.2014.0482 Fermer
30.	Demeulemeester, Morgane; Moroni, Christine; Kochman, Frederick; Thomas, Pierre; Jardri, Renaud Hallucinations et cognition : une modélisation au service de notre pratique en neuropsychologie. Article de journal Dans: Revue de Neuropsychologie, 6 (2), p. 117–128, 2014. Liens \| BibTeX @article{demeulemeester_hallucinations_2014, title = {Hallucinations et cognition : une modélisation au service de notre pratique en neuropsychologie.}, author = {Morgane Demeulemeester and Christine Moroni and Frederick Kochman and Pierre Thomas and Renaud Jardri}, doi = {10.1684/nrp.2014.0298}, year = {2014}, date = {2014-01-01}, journal = {Revue de Neuropsychologie}, volume = {6}, number = {2}, pages = {117--128}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer doi:10.1684/nrp.2014.0298 Fermer
31.	Guilbert, Alma; Clément, Sylvain; Moroni, Christine Hearing and music in unilateral spatial neglect neuro-rehabilitation Article de journal Dans: Front Psychol, 5 , p. 1503, 2014, ISSN: 1664-1078. Résumé \| Liens \| BibTeX @article{guilbert_hearing_2014, title = {Hearing and music in unilateral spatial neglect neuro-rehabilitation}, author = {Alma Guilbert and Sylvain Clément and Christine Moroni}, doi = {10.3389/fpsyg.2014.01503}, issn = {1664-1078}, year = {2014}, date = {2014-01-01}, journal = {Front Psychol}, volume = {5}, pages = {1503}, abstract = {Unilateral spatial neglect (USN) is an attention deficit in the contralesional side of space which occurs after a cerebral stroke, mainly located in the right hemisphere. USN patients are disabled in all daily activities. USN is an important negative prognostic factor of functional recovery and of socio-professional reinsertion. Thus, patient rehabilitation is a major challenge. As this deficit has been described in many sensory modalities (including hearing), many sensory and poly-sensory rehabilitation methods have been proposed to USN patients. They are mainly based on visual, tactile modalities and on motor abilities. However, these methods appear to be quite task-specific and difficult to transfer to functional activities. Very few studies have focused on the hearing modality and even fewer studies have been conducted in music as a way of improving spatial attention. Therefore, more research on such retraining needs is neccessary in order to make reliable conclusions on its efficiency in long-term rehabilitation. Nevertheless, some evidence suggests that music could be a promising tool to enhance spatial attention and to rehabilitate USN patients. In fact, music is a material closely linked to space, involving common anatomical and functional networks. The present paper aims firstly at briefly reviewing the different procedures of sensory retraining proposed in USN, including auditory retraining, and their limits. Secondly, it aims to present the recent scientific evidence that makes music a good candidate for USN patients' neuro-rehabilitation.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Unilateral spatial neglect (USN) is an attention deficit in the contralesional side of space which occurs after a cerebral stroke, mainly located in the right hemisphere. USN patients are disabled in all daily activities. USN is an important negative prognostic factor of functional recovery and of socio-professional reinsertion. Thus, patient rehabilitation is a major challenge. As this deficit has been described in many sensory modalities (including hearing), many sensory and poly-sensory rehabilitation methods have been proposed to USN patients. They are mainly based on visual, tactile modalities and on motor abilities. However, these methods appear to be quite task-specific and difficult to transfer to functional activities. Very few studies have focused on the hearing modality and even fewer studies have been conducted in music as a way of improving spatial attention. Therefore, more research on such retraining needs is neccessary in order to make reliable conclusions on its efficiency in long-term rehabilitation. Nevertheless, some evidence suggests that music could be a promising tool to enhance spatial attention and to rehabilitate USN patients. In fact, music is a material closely linked to space, involving common anatomical and functional networks. The present paper aims firstly at briefly reviewing the different procedures of sensory retraining proposed in USN, including auditory retraining, and their limits. Secondly, it aims to present the recent scientific evidence that makes music a good candidate for USN patients' neuro-rehabilitation. Fermer doi:10.3389/fpsyg.2014.01503 Fermer
32.	Boucart, Muriel; Calais, Gauthier; Lenoble, Quentin; Moroni, Christine; Pasquier, Florence Differential processing of natural scenes in posterior cortical atrophy and in Alzheimer's disease, as measured with a saccade choice task Article de journal Dans: Front Integr Neurosci, 8 , p. 60, 2014, ISSN: 1662-5145. Résumé \| Liens \| BibTeX @article{boucart_differential_2014, title = {Differential processing of natural scenes in posterior cortical atrophy and in Alzheimer's disease, as measured with a saccade choice task}, author = {Muriel Boucart and Gauthier Calais and Quentin Lenoble and Christine Moroni and Florence Pasquier}, doi = {10.3389/fnint.2014.00060}, issn = {1662-5145}, year = {2014}, date = {2014-01-01}, journal = {Front Integr Neurosci}, volume = {8}, pages = {60}, abstract = {Atrophy of the medial temporal lobe structures that support scene perception and the binding of an object to its context (i.e., the hippocampus and the parahippocampal cortex) appears early in the course of Alzheimer's disease (AD). However, few studies have investigated scene perception in people with AD. Here, we assessed the ability to find a target object within a natural scene in people with AD and in people with posterior cortical atrophy (PCA, a variant of AD). Pairs of color photographs were displayed on the left and right of a fixation cross for 1 s. In separate blocks of trials, participants were asked to categorize the target (an animal) by either moving their eyes toward the photograph containing the target (the saccadic choice task) or pressing a key corresponding to the target's location (the manual choice task). Isolated objects and objects within scenes were studied in both tasks. Participants with PCA were more impaired in detection of a target within a scene than participants with AD. The latter's performance pattern was more similar to that of age-matched controls in terms of accuracy, saccade latencies and the benefit gained from contextual information. Participants with PCA benefited less from contextual information in both the saccade and the manual choice tasks-suggesting that people with posterior brain lesions have impairments in figure/ground segregation and are more sensitive to object crowding.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Atrophy of the medial temporal lobe structures that support scene perception and the binding of an object to its context (i.e., the hippocampus and the parahippocampal cortex) appears early in the course of Alzheimer's disease (AD). However, few studies have investigated scene perception in people with AD. Here, we assessed the ability to find a target object within a natural scene in people with AD and in people with posterior cortical atrophy (PCA, a variant of AD). Pairs of color photographs were displayed on the left and right of a fixation cross for 1 s. In separate blocks of trials, participants were asked to categorize the target (an animal) by either moving their eyes toward the photograph containing the target (the saccadic choice task) or pressing a key corresponding to the target's location (the manual choice task). Isolated objects and objects within scenes were studied in both tasks. Participants with PCA were more impaired in detection of a target within a scene than participants with AD. The latter's performance pattern was more similar to that of age-matched controls in terms of accuracy, saccade latencies and the benefit gained from contextual information. Participants with PCA benefited less from contextual information in both the saccade and the manual choice tasks-suggesting that people with posterior brain lesions have impairments in figure/ground segregation and are more sensitive to object crowding. Fermer doi:10.3389/fnint.2014.00060 Fermer
33.	Haj, Mohamad El; Moroni, Christine; Luyat, Marion; Omigie, Diana; Allain, Philippe To what extent does destination recall induce episodic reliving? Evidence from Alzheimer’s disease Article de journal Dans: Journal of Clinical and Experimental Neuropsychology, 36 (2), p. 127–136, 2014, ISSN: 1380-3395. Résumé \| Liens \| BibTeX @article{haj_what_2014, title = {To what extent does destination recall induce episodic reliving? Evidence from Alzheimer’s disease}, author = {Mohamad El Haj and Christine Moroni and Marion Luyat and Diana Omigie and Philippe Allain}, url = {http://dx.doi.org/10.1080/13803395.2013.869309}, doi = {10.1080/13803395.2013.869309}, issn = {1380-3395}, year = {2014}, date = {2014-01-01}, urldate = {2015-03-26}, journal = {Journal of Clinical and Experimental Neuropsychology}, volume = {36}, number = {2}, pages = {127--136}, abstract = {We compared destination memory to source memory in patients with Alzheimer’s disease (AD), as the latter type of memory is believed to be severely deteriorated in AD. Control participants and AD patients were tested on two conditions, both of which had a study phase and a recognition phase. In the study phase of the first condition, participants had to tell a set of facts to the faces of a set of celebrities (destination memory). In the study phase of the second condition, they had to receive a different set of facts from a different set of celebrity faces (source memory). During the recognition phase, participants had to indicate, for destination memory, whether they had previously told a given fact to a given face (yes) or not (no) and, for source memory, whether they had previously received a given fact from a given face (yes) or not (no). In both conditions, they were asked to choose between “remember” or “know” options when answering “yes.” AD patients showed reliable difficulties in destination recall, accompanied by a significant decrease in the number of “remember” responses they gave. AD-related destination memory decline may be attributed to the perturbation of episodic memory and its autonoetic reliving. The potential neural bases of this decline are discussed in terms of hippocampal failures.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer We compared destination memory to source memory in patients with Alzheimer’s disease (AD), as the latter type of memory is believed to be severely deteriorated in AD. Control participants and AD patients were tested on two conditions, both of which had a study phase and a recognition phase. In the study phase of the first condition, participants had to tell a set of facts to the faces of a set of celebrities (destination memory). In the study phase of the second condition, they had to receive a different set of facts from a different set of celebrity faces (source memory). During the recognition phase, participants had to indicate, for destination memory, whether they had previously told a given fact to a given face (yes) or not (no) and, for source memory, whether they had previously received a given fact from a given face (yes) or not (no). In both conditions, they were asked to choose between “remember” or “know” options when answering “yes.” AD patients showed reliable difficulties in destination recall, accompanied by a significant decrease in the number of “remember” responses they gave. AD-related destination memory decline may be attributed to the perturbation of episodic memory and its autonoetic reliving. The potential neural bases of this decline are discussed in terms of hippocampal failures. Fermer http://dx.doi.org/10.1080/13803395.2013.869309 doi:10.1080/13803395.2013.869309 Fermer
34.	Leclercq, Eugénie; Cabaret, Maryline; Guilbert, Alma; Jougleux, Caroline; Vermersch, Patrick; Moroni, Christine Influence de la durée d’évolution de la maladie et de l’âge sur les troubles cognitifs de patients âgés atteints d’une sclérose en plaques de forme rémittente (SEP-RR) Article de journal Dans: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement, 12 (3), p. 331–338, 2014, ISSN: 2115-8789. Liens \| BibTeX @article{leclercq_influence_2014, title = {Influence de la durée d’évolution de la maladie et de l’âge sur les troubles cognitifs de patients âgés atteints d’une sclérose en plaques de forme rémittente (SEP-RR)}, author = {Eugénie Leclercq and Maryline Cabaret and Alma Guilbert and Caroline Jougleux and Patrick Vermersch and Christine Moroni}, url = {http://www.jle.com/fr/revues/gpn/e-docs/influence_de_la_duree_devolution_de_la_maladie_et_de_lage_sur_les_troubles_cognitifs_de_patients_ages_atteints_dune_sclerose_en_plaques_de_forme_remittente_sep_rr__302375/article.phtml?tab=texte}, doi = {10.1684/pnv.2014.0482}, issn = {2115-8789}, year = {2014}, date = {2014-01-01}, urldate = {2017-08-28}, journal = {Gériatrie et Psychologie Neuropsychiatrie du Vieillissement}, volume = {12}, number = {3}, pages = {331--338}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer http://www.jle.com/fr/revues/gpn/e-docs/influence_de_la_duree_devolution_de_la_m[...] doi:10.1684/pnv.2014.0482 Fermer
35.	Haj, Mohamad El; Omigie, Diana; Moroni, Christine Time reproduction during high and low attentional tasks in Alzheimer’s Disease “A watched kettle never boils” Article de journal Dans: Brain and Cognition, 88 , p. 1–5, 2014, ISSN: 02782626. Liens \| BibTeX @article{el_haj_time_2014, title = {Time reproduction during high and low attentional tasks in Alzheimer’s Disease “A watched kettle never boils”}, author = {Mohamad El Haj and Diana Omigie and Christine Moroni}, url = {http://linkinghub.elsevier.com/retrieve/pii/S0278262614000645}, doi = {10.1016/j.bandc.2014.04.002}, issn = {02782626}, year = {2014}, date = {2014-01-01}, urldate = {2017-08-28}, journal = {Brain and Cognition}, volume = {88}, pages = {1--5}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer http://linkinghub.elsevier.com/retrieve/pii/S0278262614000645 doi:10.1016/j.bandc.2014.04.002 Fermer
2013
36.	Guilbert, Alma; Feuillet, Alexia; Clément, Sylvain; Moroni, Christine Orientations exogène et endogène de l'attention en modalités visuelle et auditive dans la négligence spatiale unilatérale 5500 - 5599 Conférence 2013. BibTeX @conference{guilbert_orientations_2013, title = {Orientations exogène et endogène de l'attention en modalités visuelle et auditive dans la négligence spatiale unilatérale}, author = {Alma Guilbert and Alexia Feuillet and Sylvain Clément and Christine Moroni}, year = {2013}, date = {2013-12-01}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
37.	Guilbert, Alma; Clément, Sylvain; Séverine, Samson; Moroni, Christine Musical practice as rehabilitation method in unilateral spatial neglect 5500 - 5599 Conférence 2013. BibTeX @conference{Guilbert2013, title = {Musical practice as rehabilitation method in unilateral spatial neglect}, author = {Alma Guilbert and Sylvain Clément and Samson Séverine and Christine Moroni}, year = {2013}, date = {2013-09-01}, keywords = {}, pubstate = {published}, tppubtype = {conference} } Fermer
38.	Boucart, Muriel; Moroni, Christine; Szaffarczyk, Sebastien; Tran, Thi Ha Chau Implicit processing of scene context in macular degeneration. Article de journal Dans: Investigative ophthalmology & visual science, 54 (3), p. 1950–7, 2013, ISSN: 1552-5783. Résumé \| Liens \| BibTeX @article{boucart_implicit_2013, title = {Implicit processing of scene context in macular degeneration.}, author = {Muriel Boucart and Christine Moroni and Sebastien Szaffarczyk and Thi Ha Chau Tran}, url = {http://www.ncbi.nlm.nih.gov/pubmed/23425698}, doi = {10.1167/iovs.12-9680}, issn = {1552-5783}, year = {2013}, date = {2013-03-01}, journal = {Investigative ophthalmology & visual science}, volume = {54}, number = {3}, pages = {1950--7}, abstract = {PURPOSE: For normally sighted people, there is a general consensus that objects that appear in a congruent context (e.g., a hair dryer in a bathroom) are processed more accurately and/or more quickly than objects in an incongruent context (e.g., a hair dryer in a corn field). We investigated whether people with AMD, who have impairments in recognizing objects embedded in complex scenes, can nevertheless take advantage of contextual information for object detection. METHODS: TWENTY-TWO PEOPLE WITH AMD AND 18 AGE-MATCHED, NORMALLY SIGHTED CONTROLS TOOK PART IN THE STUDY. THEY WERE TESTED IN TWO TASKS: (1) an object detection task in which a foreground target object was set within a congruent background or an incongruent background, with no information being given to the participants as to the relationship between the target and its background, and (2) a task in which the participant had to explicitly state whether or not the foreground object was congruent with its background. A go/no-go paradigm was used in both tasks (i.e., a key press when the target is present and no key press when it is absent). The same participants, stimuli, and presentation conditions were used in both tasks. RESULTS: In the context task, the people with AMD exhibited higher sensitivity when the target object was consistent with its background; however, they performed no better than chance in the explicit task. Normally sighted controls benefited from the congruent context in both tasks. CONCLUSIONS: Our results suggest that when central vision is impaired (as in AMD), the contextual information captured by peripheral vision provides cues for object categorization.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer PURPOSE: For normally sighted people, there is a general consensus that objects that appear in a congruent context (e.g., a hair dryer in a bathroom) are processed more accurately and/or more quickly than objects in an incongruent context (e.g., a hair dryer in a corn field). We investigated whether people with AMD, who have impairments in recognizing objects embedded in complex scenes, can nevertheless take advantage of contextual information for object detection. METHODS: TWENTY-TWO PEOPLE WITH AMD AND 18 AGE-MATCHED, NORMALLY SIGHTED CONTROLS TOOK PART IN THE STUDY. THEY WERE TESTED IN TWO TASKS: (1) an object detection task in which a foreground target object was set within a congruent background or an incongruent background, with no information being given to the participants as to the relationship between the target and its background, and (2) a task in which the participant had to explicitly state whether or not the foreground object was congruent with its background. A go/no-go paradigm was used in both tasks (i.e., a key press when the target is present and no key press when it is absent). The same participants, stimuli, and presentation conditions were used in both tasks. RESULTS: In the context task, the people with AMD exhibited higher sensitivity when the target object was consistent with its background; however, they performed no better than chance in the explicit task. Normally sighted controls benefited from the congruent context in both tasks. CONCLUSIONS: Our results suggest that when central vision is impaired (as in AMD), the contextual information captured by peripheral vision provides cues for object categorization. Fermer http://www.ncbi.nlm.nih.gov/pubmed/23425698 doi:10.1167/iovs.12-9680 Fermer
39.	Delbeuck, Xavier; Debachy, Brigitte; Pasquier, Florence; Moroni, Christine Action and noun fluency testing to distinguish between Alzheimer's disease and dementia with Lewy bodies Article de journal Dans: Journal of Clinical and Experimental Neuropsychology, 35 (3), p. 259–268, 2013, ISSN: 1380-3395. Résumé \| Liens \| BibTeX @article{delbeuck_action_2013, title = {Action and noun fluency testing to distinguish between Alzheimer's disease and dementia with Lewy bodies}, author = {Xavier Delbeuck and Brigitte Debachy and Florence Pasquier and Christine Moroni}, url = {http://dx.doi.org/10.1080/13803395.2013.763907}, doi = {10.1080/13803395.2013.763907}, issn = {1380-3395}, year = {2013}, date = {2013-03-01}, urldate = {2015-03-26}, journal = {Journal of Clinical and Experimental Neuropsychology}, volume = {35}, number = {3}, pages = {259--268}, abstract = {The objective of the present study was to establish whether performance in an action fluency task is of value in the differential diagnosis of Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). After collecting normative data on performance in an action fluency task and a conventional animal fluency task in a cohort of French-speaking healthy controls, we assessed AD and DLB patients. Only the action fluency score differed significantly between the two demented groups, with DLB patients performing worse than AD patients. However, a composite action and animal fluency score was found to be more effective for discriminating between these two groups.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer The objective of the present study was to establish whether performance in an action fluency task is of value in the differential diagnosis of Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). After collecting normative data on performance in an action fluency task and a conventional animal fluency task in a cohort of French-speaking healthy controls, we assessed AD and DLB patients. Only the action fluency score differed significantly between the two demented groups, with DLB patients performing worse than AD patients. However, a composite action and animal fluency score was found to be more effective for discriminating between these two groups. Fermer http://dx.doi.org/10.1080/13803395.2013.763907 doi:10.1080/13803395.2013.763907 Fermer
40.	Godefroy, O; Leclercq, C; Bugnicourt, J -M; Roussel, M; Moroni, C; Quaglino, V; Beaunieux, H; Taillia, H; Nédélec-Ciceri, C; Bonnin, C; Thomas-Anterion, C; Varvat, J; Aboulafia-Brakha, T; Assal, F Neuropsychological assessment and cerebral vascular disease: the new standards. Article de journal Dans: Revue neurologique, 169 (10), p. 779–85, 2013, ISSN: 0035-3787. Résumé \| Liens \| BibTeX @article{godefroy_neuropsychological_2013, title = {Neuropsychological assessment and cerebral vascular disease: the new standards.}, author = {O Godefroy and C Leclercq and J -M Bugnicourt and M Roussel and C Moroni and V Quaglino and H Beaunieux and H Taillia and C Nédélec-Ciceri and C Bonnin and C Thomas-Anterion and J Varvat and T Aboulafia-Brakha and F Assal}, url = {http://www.ncbi.nlm.nih.gov/pubmed/23999023}, doi = {10.1016/j.neurol.2013.07.009}, issn = {0035-3787}, year = {2013}, date = {2013-01-01}, journal = {Revue neurologique}, volume = {169}, number = {10}, pages = {779--85}, abstract = {Vascular cognitive impairment (VCI) includes vascular dementia (VaD), vascular mild cognitive impairment (VaMCI) and mixed dementia. In clinical practice, VCI concerns patients referred for clinical stroke or cognitive complaint. To improve the characterization of VCI and to refine its diagnostic criteria, an international group has elaborated a new standardized evaluation battery of clinical, cognitive, behavioral and neuroradiological data which now constitutes the reference battery. The adaption of the battery for French-speaking subjects is reported as well as preliminary results of the on-going validation study of the GRECOG-VASC group [Clinical Trial NCT01339195]. The diagnostic accuracy of various screening tests is reviewed and showed an overall sub-optimal sensitivity (textless0.8). Thus, the general recommendation is to perform systematically a comprehensive assessment in stroke patients at risk of VCI. Furthermore,the use of a structured interview has been shown to increase the detection of dementia. In addition to the well known NINDS-AIREN criteria of VaD, criteria of VCI have been recently proposed which are based on the demonstration of a cognitive disorder by neuropsychological testing and either history of clinical stroke or presence of vascular lesion by neuroimaging suggestive of a link between cognitive impairment and vascular disease. A memory deficit is no longer required for the diagnosis of VaD as it is based on the cognitive decline concerning two or more domains that affect activities of daily living. Both VaMCI and VaD are classified as probable or possible. These new criteria have yet to be validated. Considerable uncertainties remain regarding the determinant of VCI, and especially the lesion amount inducing VCI and VaD. The interaction between lesion amount and its location is currently re-examined using recent techniques for the analysis of MRI data. The high frequency of associated Alzheimer pathology is now assessable in vivo using amyloid imaging. The first studies showed that about a third of patients with VaD due to small vessel disease or with poststroke dementia have amyloid PET imaging suggestive of AD. These new techniques will examine the interaction between vascular lesions and promotion of amyloid deposition. Although results of these on-going studies will be available in few years, these data indicate that efforts should be done in clinical practice to reduce underdiagnosis of VCI; VCI should be examined using a specific protocol which will be fully normalized soon for French-speaking patients; the sub-optimal sensitivity of screening tests prompts to use a structured interview to grade Rankin scale and to perform systematically a comprehensive assessment in stroke patients at risk of VCI; poststroke dementia occurring after 3 months poststroke may be preventable by treatment of modifiable vascular risk factors and secondary prevention of stroke recurrence according to recent recommendations.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Vascular cognitive impairment (VCI) includes vascular dementia (VaD), vascular mild cognitive impairment (VaMCI) and mixed dementia. In clinical practice, VCI concerns patients referred for clinical stroke or cognitive complaint. To improve the characterization of VCI and to refine its diagnostic criteria, an international group has elaborated a new standardized evaluation battery of clinical, cognitive, behavioral and neuroradiological data which now constitutes the reference battery. The adaption of the battery for French-speaking subjects is reported as well as preliminary results of the on-going validation study of the GRECOG-VASC group [Clinical Trial NCT01339195]. The diagnostic accuracy of various screening tests is reviewed and showed an overall sub-optimal sensitivity (textless0.8). Thus, the general recommendation is to perform systematically a comprehensive assessment in stroke patients at risk of VCI. Furthermore,the use of a structured interview has been shown to increase the detection of dementia. In addition to the well known NINDS-AIREN criteria of VaD, criteria of VCI have been recently proposed which are based on the demonstration of a cognitive disorder by neuropsychological testing and either history of clinical stroke or presence of vascular lesion by neuroimaging suggestive of a link between cognitive impairment and vascular disease. A memory deficit is no longer required for the diagnosis of VaD as it is based on the cognitive decline concerning two or more domains that affect activities of daily living. Both VaMCI and VaD are classified as probable or possible. These new criteria have yet to be validated. Considerable uncertainties remain regarding the determinant of VCI, and especially the lesion amount inducing VCI and VaD. The interaction between lesion amount and its location is currently re-examined using recent techniques for the analysis of MRI data. The high frequency of associated Alzheimer pathology is now assessable in vivo using amyloid imaging. The first studies showed that about a third of patients with VaD due to small vessel disease or with poststroke dementia have amyloid PET imaging suggestive of AD. These new techniques will examine the interaction between vascular lesions and promotion of amyloid deposition. Although results of these on-going studies will be available in few years, these data indicate that efforts should be done in clinical practice to reduce underdiagnosis of VCI; VCI should be examined using a specific protocol which will be fully normalized soon for French-speaking patients; the sub-optimal sensitivity of screening tests prompts to use a structured interview to grade Rankin scale and to perform systematically a comprehensive assessment in stroke patients at risk of VCI; poststroke dementia occurring after 3 months poststroke may be preventable by treatment of modifiable vascular risk factors and secondary prevention of stroke recurrence according to recent recommendations. Fermer http://www.ncbi.nlm.nih.gov/pubmed/23999023 doi:10.1016/j.neurol.2013.07.009 Fermer
41.	Haj, Mohamad El; Moroni, Christine; Samson, Séverine; Fasotti, Luciano; Allain, Philippe Prospective and retrospective time perception are related to mental time travel: Evidence from Alzheimer’s disease Article de journal Dans: Brain and Cognition, 83 (1), p. 45–51, 2013, ISSN: 0278-2626. Résumé \| Liens \| BibTeX @article{haj_prospective_2013, title = {Prospective and retrospective time perception are related to mental time travel: Evidence from Alzheimer’s disease}, author = {Mohamad El Haj and Christine Moroni and Séverine Samson and Luciano Fasotti and Philippe Allain}, url = {http://www.sciencedirect.com/science/article/pii/S0278262613000882}, doi = {10.1016/j.bandc.2013.06.008}, issn = {0278-2626}, year = {2013}, date = {2013-01-01}, urldate = {2015-03-26}, journal = {Brain and Cognition}, volume = {83}, number = {1}, pages = {45--51}, abstract = {Unlike prospective time perception paradigms, in which participants are aware that they have to estimate forthcoming time, little is known about retrospective time perception in normal aging and Alzheimer’s disease (AD). Our paper addresses this shortcoming by comparing prospective and retrospective time estimation in younger adults, older adults, and AD patients. In four prospective tasks (lasting 30 s, 60 s, 90 s, or 120 s) participants were asked to read a series of numbers and to provide a verbal estimation of the reading time. In four other retrospective tasks, they were not informed about time judgment until they were asked to provide a verbal estimation of four elapsed time intervals (lasting 30 s, 60 s, 90 s, or 120 s). AD participants gave shorter verbal time estimations than older adults and younger participants did, suggesting that time is perceived to pass quickly in these patients. For all participants, the duration of the retrospective tasks was underestimated as compared to the prospective tasks and both estimations were shorter than the real time interval. Prospective time estimation was further correlated with mental time travel, as measured with the Remember/Know paradigm. Mental time travel was even higher correlated with retrospective time estimation. Our findings shed light on the relationship between time perception and the ability to mentally project oneself into time, two skills contributing to human memory functioning. Finally, time perception deficits, as observed in AD patients, can be interpreted in terms of dramatic changes occurring in frontal lobes and hippocampus.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Unlike prospective time perception paradigms, in which participants are aware that they have to estimate forthcoming time, little is known about retrospective time perception in normal aging and Alzheimer’s disease (AD). Our paper addresses this shortcoming by comparing prospective and retrospective time estimation in younger adults, older adults, and AD patients. In four prospective tasks (lasting 30 s, 60 s, 90 s, or 120 s) participants were asked to read a series of numbers and to provide a verbal estimation of the reading time. In four other retrospective tasks, they were not informed about time judgment until they were asked to provide a verbal estimation of four elapsed time intervals (lasting 30 s, 60 s, 90 s, or 120 s). AD participants gave shorter verbal time estimations than older adults and younger participants did, suggesting that time is perceived to pass quickly in these patients. For all participants, the duration of the retrospective tasks was underestimated as compared to the prospective tasks and both estimations were shorter than the real time interval. Prospective time estimation was further correlated with mental time travel, as measured with the Remember/Know paradigm. Mental time travel was even higher correlated with retrospective time estimation. Our findings shed light on the relationship between time perception and the ability to mentally project oneself into time, two skills contributing to human memory functioning. Finally, time perception deficits, as observed in AD patients, can be interpreted in terms of dramatic changes occurring in frontal lobes and hippocampus. Fermer http://www.sciencedirect.com/science/article/pii/S0278262613000882 doi:10.1016/j.bandc.2013.06.008 Fermer
42.	Boucart, Muriel; Moroni, Christine; Thibaut, Miguel; Szaffarczyk, Sebastien; Greene, Michelle Scene categorization at large visual eccentricities Article de journal Dans: Vision Research, 86 , p. 35–42, 2013, ISSN: 0042-6989. Résumé \| Liens \| BibTeX @article{boucart_scene_2013, title = {Scene categorization at large visual eccentricities}, author = {Muriel Boucart and Christine Moroni and Miguel Thibaut and Sebastien Szaffarczyk and Michelle Greene}, url = {http://www.sciencedirect.com/science/article/pii/S0042698913000977}, doi = {10.1016/j.visres.2013.04.006}, issn = {0042-6989}, year = {2013}, date = {2013-01-01}, urldate = {2015-03-26}, journal = {Vision Research}, volume = {86}, pages = {35--42}, abstract = {Studies of scene perception have shown that the visual system is particularly sensitive to global properties such as the overall layout of a scene. Such global properties cannot be computed locally, but rather require relational analysis over multiple regions. To what extent is observers’ perception of scenes impaired in the far periphery? We examined the perception of global scene properties (Experiment 1) and basic-level categories (Experiment 2) presented in the periphery from 10° to 70°. Pairs of scene photographs were simultaneously presented left and right of fixation for 80 ms on a panoramic screen (5 m diameter) covering the whole visual field while central fixation was controlled. Observers were instructed to press a key corresponding to the spatial location left/right of a pre-defined target property or category. The results show that classification of global scene properties (e.g., naturalness, openness) as well as basic-level categorization (e.g., forests, highways), while better near the center, were accomplished with a performance highly above chance (around 70% correct) in the far periphery even at 70° eccentricity. The perception of some global properties (e.g., naturalness) was more robust in peripheral vision than others (e.g., indoor/outdoor) that required a more local analysis. The results are consistent with studies suggesting that scene gist recognition can be accomplished by the low resolution of peripheral vision.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Studies of scene perception have shown that the visual system is particularly sensitive to global properties such as the overall layout of a scene. Such global properties cannot be computed locally, but rather require relational analysis over multiple regions. To what extent is observers’ perception of scenes impaired in the far periphery? We examined the perception of global scene properties (Experiment 1) and basic-level categories (Experiment 2) presented in the periphery from 10° to 70°. Pairs of scene photographs were simultaneously presented left and right of fixation for 80 ms on a panoramic screen (5 m diameter) covering the whole visual field while central fixation was controlled. Observers were instructed to press a key corresponding to the spatial location left/right of a pre-defined target property or category. The results show that classification of global scene properties (e.g., naturalness, openness) as well as basic-level categorization (e.g., forests, highways), while better near the center, were accomplished with a performance highly above chance (around 70% correct) in the far periphery even at 70° eccentricity. The perception of some global properties (e.g., naturalness) was more robust in peripheral vision than others (e.g., indoor/outdoor) that required a more local analysis. The results are consistent with studies suggesting that scene gist recognition can be accomplished by the low resolution of peripheral vision. Fermer http://www.sciencedirect.com/science/article/pii/S0042698913000977 doi:10.1016/j.visres.2013.04.006 Fermer
2011
43.	Baubet, Thierry; Ranque, Brigitte; Taïeb, Olivier; Bérezné, Alice; Bricou, Olivier; Mehallel, Salim; Moroni, Christine; Belin, Catherine; Pagnoux, Christian; Moro, Marie-Rose; Guillevin, Loïc; Mouthon, Luc Mood and anxiety disorders in systemic sclerosis patients. Article de journal Dans: Presse médicale (Paris, France : 1983), 40 (2), p. e111–9, 2011, ISSN: 0755-4982. Résumé \| Liens \| BibTeX @article{baubet_mood_2011, title = {Mood and anxiety disorders in systemic sclerosis patients.}, author = {Thierry Baubet and Brigitte Ranque and Olivier Taïeb and Alice Bérezné and Olivier Bricou and Salim Mehallel and Christine Moroni and Catherine Belin and Christian Pagnoux and Marie-Rose Moro and Loïc Guillevin and Luc Mouthon}, url = {http://www.ncbi.nlm.nih.gov/pubmed/21055901}, doi = {10.1016/j.lpm.2010.09.019}, issn = {0755-4982}, year = {2011}, date = {2011-01-01}, journal = {Presse médicale (Paris, France : 1983)}, volume = {40}, number = {2}, pages = {e111--9}, abstract = {OBJECTIVE: To assess the prevalence of mood and anxiety disorders in systemic sclerosis (SSc) patients and the association of these disorders with clinical features. METHODS: Between May 2002 and May 2004, 100 SSc patients fulfilling the American Rheumatism Association and/or Leroy & Medsger criteria were recruited: 51 were from a SSc patient association meeting, and 49 were hospitalized in an internal medicine department and recruited consecutively. Mood and anxiety disorders were assessed by use of a structured clinical interview [the Mini International Neuropsychiatric Interview (MINI)] performed by a psychiatrist and a self-reporting questionnaire [the Hospital Anxiety and Depression Scale (HADS)]. On the same day, psychiatric treatment and clinical features were recorded by a physician. RESULTS: As assessed by the MINI, 19% [95% confidence interval 12-28%] of all SSc patients were currently experiencing a major depressive episode (MDE), 56% [46-65%] had a lifetime history of MDE and 14% [8-22%] had current dysthymia. Current MDE was more prevalent among hospitalized patients than among other patients (28% versus 10%}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer OBJECTIVE: To assess the prevalence of mood and anxiety disorders in systemic sclerosis (SSc) patients and the association of these disorders with clinical features. METHODS: Between May 2002 and May 2004, 100 SSc patients fulfilling the American Rheumatism Association and/or Leroy & Medsger criteria were recruited: 51 were from a SSc patient association meeting, and 49 were hospitalized in an internal medicine department and recruited consecutively. Mood and anxiety disorders were assessed by use of a structured clinical interview [the Mini International Neuropsychiatric Interview (MINI)] performed by a psychiatrist and a self-reporting questionnaire [the Hospital Anxiety and Depression Scale (HADS)]. On the same day, psychiatric treatment and clinical features were recorded by a physician. RESULTS: As assessed by the MINI, 19% [95% confidence interval 12-28%] of all SSc patients were currently experiencing a major depressive episode (MDE), 56% [46-65%] had a lifetime history of MDE and 14% [8-22%] had current dysthymia. Current MDE was more prevalent among hospitalized patients than among other patients (28% versus 10% Fermer http://www.ncbi.nlm.nih.gov/pubmed/21055901 doi:10.1016/j.lpm.2010.09.019 Fermer
44.	Bayard, Sophie; Erkes, Jérôme; Moroni, Christine; the des spécialisés en du Roussillon), Collège Psychologues Cliniciens Neuropsychologie Languedoc Roussillon (CPCN Languedoc Victoria Stroop Test: Normative Data in a Sample Group of Older People and the Study of Their Clinical Applications in the Assessment of Inhibition in Alzheimer's Disease Article de journal Dans: Arch Clin Neuropsychol, p. acr053, 2011, ISSN: 0887-6177, 1873-5843. Résumé \| Liens \| BibTeX @article{bayard_victoria_2011, title = {Victoria Stroop Test: Normative Data in a Sample Group of Older People and the Study of Their Clinical Applications in the Assessment of Inhibition in Alzheimer's Disease}, author = {Sophie Bayard and Jérôme Erkes and Christine Moroni and Collège Psychologues Cliniciens Neuropsychologie Languedoc Roussillon (CPCN Languedoc the des spécialisés en du Roussillon)}, url = {http://acn.oxfordjournals.org/content/early/2011/08/26/arclin.acr053}, doi = {10.1093/arclin/acr053}, issn = {0887-6177, 1873-5843}, year = {2011}, date = {2011-01-01}, urldate = {2015-03-26}, journal = {Arch Clin Neuropsychol}, pages = {acr053}, abstract = {The Stroop Color-Word Test-Victoria version (VST) is a measure of executive function commonly used in neuropsychological evaluation. Because of its short administration time, the VST seems particularly appropriate for use in geriatric populations and with those suffering from dementia and who are prone to fatigue during neuropsychological examination. In this study, we examine the influence of demographic characteristics on VST score and present descriptive data for a sample of 244 elderly French speakers (50–94 years of age). Normative data corrected for age and education are provided for clinical use. Furthermore, by comparing the VST performance of patients with the Alzheimer-type dementia to that of 40 matched healthy controls, we provide clinical evidence suggesting that the VST has a clinical utility in the assessment of inhibition in AD.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer The Stroop Color-Word Test-Victoria version (VST) is a measure of executive function commonly used in neuropsychological evaluation. Because of its short administration time, the VST seems particularly appropriate for use in geriatric populations and with those suffering from dementia and who are prone to fatigue during neuropsychological examination. In this study, we examine the influence of demographic characteristics on VST score and present descriptive data for a sample of 244 elderly French speakers (50–94 years of age). Normative data corrected for age and education are provided for clinical use. Furthermore, by comparing the VST performance of patients with the Alzheimer-type dementia to that of 40 matched healthy controls, we provide clinical evidence suggesting that the VST has a clinical utility in the assessment of inhibition in AD. Fermer http://acn.oxfordjournals.org/content/early/2011/08/26/arclin.acr053 doi:10.1093/arclin/acr053 Fermer
2010
45.	Rémy, Ludovic; Moroni, Christine Comparaison de trois formes abrégées de l’échelle d’intelligence de Wechsler pour adultes (WAIS-III) In A. De Ribaupierre, P. Ghisletta, Ŧ. Lecerf, J.-L. Roulin (dir), Identité et spécificités de la psychologie différentielle (p.449-454). Article de journal Dans: Presses Universitaires de Rennes, p. 449–454, 2010. BibTeX @article{remy_comparaison_2010, title = {Comparaison de trois formes abrégées de l’échelle d’intelligence de Wechsler pour adultes (WAIS-III) In A. De Ribaupierre, P. Ghisletta, Ŧ. Lecerf, J.-L. Roulin (dir), Identité et spécificités de la psychologie différentielle (p.449-454).}, author = {Ludovic Rémy and Christine Moroni}, year = {2010}, date = {2010-04-01}, journal = {Presses Universitaires de Rennes}, pages = {449--454}, series = {Presses Universitaires de Rennes.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer
46.	Boucart, Muriel; Moroni, Christine; Despretz, Pascal; Pasquier, Florence; Fabre-Thorpe, Michele Rapid categorization of faces and objects in a patient with impaired object recognition Article de journal Dans: Neurocase, 16 (2), p. 157–168, 2010, ISSN: 1355-4794. Résumé \| Liens \| BibTeX @article{boucart_rapid_2010, title = {Rapid categorization of faces and objects in a patient with impaired object recognition}, author = {Muriel Boucart and Christine Moroni and Pascal Despretz and Florence Pasquier and Michele Fabre-Thorpe}, url = {http://dx.doi.org/10.1080/13554790903339637}, doi = {10.1080/13554790903339637}, issn = {1355-4794}, year = {2010}, date = {2010-03-01}, urldate = {2015-03-26}, journal = {Neurocase}, volume = {16}, number = {2}, pages = {157--168}, abstract = {We tested rapid-categorization in a patient who was impaired in face and object recognition. Photographs of natural scenes were displayed for 100 ms. Participants had to press a key when they saw an animal among various objects as distractors or human faces among animal faces as distractors. Though the patient was impaired at figure/ground segregation, recognized very few objects and faces, she categorized animals and faces with a performance ranging between 70 and 86% correct. Displaying pictures in isolation did not improve performance. The results suggest that rapid categorization can be accomplished on the basis of coarse information without overt recognition.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer We tested rapid-categorization in a patient who was impaired in face and object recognition. Photographs of natural scenes were displayed for 100 ms. Participants had to press a key when they saw an animal among various objects as distractors or human faces among animal faces as distractors. Though the patient was impaired at figure/ground segregation, recognized very few objects and faces, she categorized animals and faces with a performance ranging between 70 and 86% correct. Displaying pictures in isolation did not improve performance. The results suggest that rapid categorization can be accomplished on the basis of coarse information without overt recognition. Fermer http://dx.doi.org/10.1080/13554790903339637 doi:10.1080/13554790903339637 Fermer
47.	Veronique, Le Guern; C, Belin; C, Henegar; Christine, Moroni; Didier, Maillet; C, Lacau; Louis, Dumas Jean; N, Vigneron; L, Guillevin Cognitive function and 99mTc-ECD brain SPECT are significantly correlated in patients with primary Sjögren syndrome: a case–control study Article de journal Dans: Ann Rheum Dis, 69 (01), p. 132–137, 2010, ISSN: , 1468-2060. Résumé \| Liens \| BibTeX @article{veronique_cognitive_2010, title = {Cognitive function and 99mTc-ECD brain SPECT are significantly correlated in patients with primary Sjögren syndrome: a case–control study}, author = {Le Guern Veronique and Belin C and Henegar C and Moroni Christine and Maillet Didier and Lacau C and Dumas Jean Louis and Vigneron N and Guillevin L}, url = {http://ard.bmj.com/content/69/01/132}, doi = {10.1136/ard.2008.090811}, issn = {, 1468-2060}, year = {2010}, date = {2010-01-01}, urldate = {2015-03-26}, journal = {Ann Rheum Dis}, volume = {69}, number = {01}, pages = {132--137}, abstract = {Objectives: To assess subclinical central nervous system (CNS) involvement in primary Sjögren syndrome (pSS), by comparing standard brain MRI, in-depth neuropsychological testing and 99mTc-ECD brain single-photon emission computed tomography (SPECT) of patients with pSS with matched controls. Methods: 10 women (textless55 years old), with pSS defined using European–American criteria, presence of anti-SSA and/or anti-SSB antibodies and no history of neurological involvement were prospectively investigated, and compared with 10 age- and sex-matched controls. All subjects underwent, within 1 month, brain MRI, neuropsychological testing, including overall evaluation and focal cognitive function assessment, and 99mTc-ECD brain SPECT. Results: 99mTc-ECD brain SPECT abnormalities were significantly more common in patients with pSS (10/10) than controls (2/10; ptextless0.05). Cognitive dysfunctions, mainly expressed as executive and visuospatial disorders, were also significantly more common in patients with pSS (8/10) than controls (0/10; ptextless0.01). Notably, between-group comparisons enabled a significant correlation to be established between neuropsychological assessment and 99mTc-ECD brain SPECT abnormalities in patients with pSS (rs = 0.49, ptextless0.01). MRI abnormalities in patients and controls did not differ significantly. Conclusions: Neuropsychological testing and 99mTc-ECD brain SPECT seem to be the most sensitive tools to detect subclinical CNS dysfunction in pSS. The strong correlation between cortical hypoperfusion in 99mTc-ECD brain SPECT and cognitive dysfunction suggests an organic aetiology of CNS dysfunction in pSS. These data should be confirmed in a larger study.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Objectives: To assess subclinical central nervous system (CNS) involvement in primary Sjögren syndrome (pSS), by comparing standard brain MRI, in-depth neuropsychological testing and 99mTc-ECD brain single-photon emission computed tomography (SPECT) of patients with pSS with matched controls. Methods: 10 women (textless55 years old), with pSS defined using European–American criteria, presence of anti-SSA and/or anti-SSB antibodies and no history of neurological involvement were prospectively investigated, and compared with 10 age- and sex-matched controls. All subjects underwent, within 1 month, brain MRI, neuropsychological testing, including overall evaluation and focal cognitive function assessment, and 99mTc-ECD brain SPECT. Results: 99mTc-ECD brain SPECT abnormalities were significantly more common in patients with pSS (10/10) than controls (2/10; ptextless0.05). Cognitive dysfunctions, mainly expressed as executive and visuospatial disorders, were also significantly more common in patients with pSS (8/10) than controls (0/10; ptextless0.01). Notably, between-group comparisons enabled a significant correlation to be established between neuropsychological assessment and 99mTc-ECD brain SPECT abnormalities in patients with pSS (rs = 0.49, ptextless0.01). MRI abnormalities in patients and controls did not differ significantly. Conclusions: Neuropsychological testing and 99mTc-ECD brain SPECT seem to be the most sensitive tools to detect subclinical CNS dysfunction in pSS. The strong correlation between cortical hypoperfusion in 99mTc-ECD brain SPECT and cognitive dysfunction suggests an organic aetiology of CNS dysfunction in pSS. These data should be confirmed in a larger study. Fermer http://ard.bmj.com/content/69/01/132 doi:10.1136/ard.2008.090811 Fermer
2009
48.	Mahieux-Laurent, F; Fabre, C; Galbrun, E; Dubrulle, A; Moroni, C [Validation of a brief screening scale evaluating praxic abilities for use in memory clinics. Evaluation in 419 controls, 127 mild cognitive impairment and 320 demented patients]. Article de journal Dans: Revue neurologique, 165 (6-7), p. 560–7, 2009, ISSN: 0035-3787. Résumé \| Liens \| BibTeX @article{mahieux-laurent_[validation_2009, title = {[Validation of a brief screening scale evaluating praxic abilities for use in memory clinics. Evaluation in 419 controls, 127 mild cognitive impairment and 320 demented patients].}, author = {F Mahieux-Laurent and C Fabre and E Galbrun and A Dubrulle and C Moroni}, url = {http://www.ncbi.nlm.nih.gov/pubmed/19150097}, doi = {10.1016/j.neurol.2008.11.016}, issn = {0035-3787}, year = {2009}, date = {2009-01-01}, journal = {Revue neurologique}, volume = {165}, number = {6-7}, pages = {560--7}, abstract = {INTRODUCTION: The aim of this study was to build a brief clinical scale evaluating praxic abilities of the upper limbs for use in memory clinics and to produce norms. PATIENTS AND METHODS: The scale includes three subtests: symbolic gestures (five gestures), pantomimes (five gestures) and imitation of meaningless gestures (eight gestures). Data were collected in a sample of 419 normal subjects. Sensitivity and specificity were established from their comparison to data collected from 320 demented patients. A group of 127 patients with mild cognitive impairment was also studied. RESULTS: Cut-off scores were proposed based on the fifth percentile observed in three classes of age and three levels of education. The specificity was high. Sensitivity was higher for imitation of meaningless gestures than for pantomimes and the least for symbolic gestures. The group of patients with mild cognitive impairment was half-way between demented patients and normal subjects. CONCLUSION: The proposed scale meets its initial aims of brevity and high specificity. It can easily be used in memory clinics and identifies apraxia in dementia patients. It therefore usefully contributes to clinical diagnosis.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer INTRODUCTION: The aim of this study was to build a brief clinical scale evaluating praxic abilities of the upper limbs for use in memory clinics and to produce norms. PATIENTS AND METHODS: The scale includes three subtests: symbolic gestures (five gestures), pantomimes (five gestures) and imitation of meaningless gestures (eight gestures). Data were collected in a sample of 419 normal subjects. Sensitivity and specificity were established from their comparison to data collected from 320 demented patients. A group of 127 patients with mild cognitive impairment was also studied. RESULTS: Cut-off scores were proposed based on the fifth percentile observed in three classes of age and three levels of education. The specificity was high. Sensitivity was higher for imitation of meaningless gestures than for pantomimes and the least for symbolic gestures. The group of patients with mild cognitive impairment was half-way between demented patients and normal subjects. CONCLUSION: The proposed scale meets its initial aims of brevity and high specificity. It can easily be used in memory clinics and identifies apraxia in dementia patients. It therefore usefully contributes to clinical diagnosis. Fermer http://www.ncbi.nlm.nih.gov/pubmed/19150097 doi:10.1016/j.neurol.2008.11.016 Fermer
49.	Maillet, Didier; Moroni, Christine; Belin, Catherine L’atrophie corticale postérieure Article de journal Dans: Psychologie et Neuropsychiatrie du vieillissement, 3 , p. 193–203, 2009. BibTeX @article{maillet_latrophie_2009, title = {L’atrophie corticale postérieure}, author = {Didier Maillet and Christine Moroni and Catherine Belin}, year = {2009}, date = {2009-01-01}, journal = {Psychologie et Neuropsychiatrie du vieillissement}, volume = {3}, pages = {193--203}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer
50.	Hommet, Caroline; Beauchet, Olivier; Moroni, Christine; Mondon, Karl; Perrier, Danièle; Berrut, Gilles; Constans, Thierry [Cerebral lateralization and hemispheric interaction in aging: what about dichotic listening?]. Article de journal Dans: Psychologie & neuropsychiatrie du vieillissement, 7 (1), p. 65–72, 2009, ISSN: 1760-1703. Résumé \| Liens \| BibTeX @article{hommet_[cerebral_2009, title = {[Cerebral lateralization and hemispheric interaction in aging: what about dichotic listening?].}, author = {Caroline Hommet and Olivier Beauchet and Christine Moroni and Karl Mondon and Danièle Perrier and Gilles Berrut and Thierry Constans}, url = {http://www.ncbi.nlm.nih.gov/pubmed/19251573}, doi = {10.1684/pnv.2009.0158}, issn = {1760-1703}, year = {2009}, date = {2009-01-01}, journal = {Psychologie & neuropsychiatrie du vieillissement}, volume = {7}, number = {1}, pages = {65--72}, abstract = {Dichotic listening is the most frequent behavioral test used to assess hemispheric lateralization. The subjects simultaneously receive competing information signals in each ear and the attention resources are mobilized. Dichotic listening may be viewed as a dual-task procedure. In fact, executive functions and attention, which are involved, may be modified in elderly. The aim of this paper is to define the role of dichotic listening for the study of hemispheric interactions in the elderly, according to compensation/reorganization processes in normal and pathological aging.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Fermer Dichotic listening is the most frequent behavioral test used to assess hemispheric lateralization. The subjects simultaneously receive competing information signals in each ear and the attention resources are mobilized. Dichotic listening may be viewed as a dual-task procedure. In fact, executive functions and attention, which are involved, may be modified in elderly. The aim of this paper is to define the role of dichotic listening for the study of hemispheric interactions in the elderly, according to compensation/reorganization processes in normal and pathological aging. Fermer http://www.ncbi.nlm.nih.gov/pubmed/19251573 doi:10.1684/pnv.2009.0158 Fermer

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Moroni C

Professeur des Universités Neuropsychologie

♦ Thèmes de TE et TER | 2017-18 ♦

1) Evaluer des capacités d’inhibition et de flexibilité mentale :

2) SEP et Vieillissement :

3) Evaluation des capacités de mémoire de travail :

1) Intérêt des corrélations anatomo-cliniques chez les patients présentant une pathologie dégénérative :

2) Répartition des capacités d’attention visuelle en cas d’atteinte du champ visuel :

3) Mémoire sémantique : Intérêt d’une procédure rapide d’évaluation.

♦ Encadrement de thèse ♦

♦ liens utiles en relation avec la neuropsychologie ♦

♦ Matériel de test ♦

♦ Publication ♦

♦ Publications ♦

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Professeur des Universités
Neuropsychologie