Professeur des Universités
Neuropsychologie
Université Lille 3
Domaine Universitaire du Pont de Bois
BP 60149
59653 Villeneuve d’Ascq Cedex
Bureau : A5.327
♦ Thèmes de TE et TER | 2017-18 ♦
Contact par mail : christine.moroni@univ-lille3.fr
- Thèmes de TE – Etudiants en 3ième année de Licence
1) Evaluer des capacités d’inhibition et de flexibilité mentale :
Evaluer les capacités d’inhibition et de flexibilité mentale peut se révéler difficile chez des patients qui ont été peu scolarisés ou qui ne maîtrisent pas correctement le français. Le Five Digit Test (FDT) permet cette évaluation, toutefois il n’existe pas de normes contrôles pour la population française.
L’objectif de ce travail d’études pour l’année 2017-18 sera de compléter le recueil de données contrôles pour cette épreuve neuropsychologique et cela auprès d’une population tout venant (francophone ou non, scolarisée ou non….) dans le but de permettre la normalisation de cet outil et ainsi permettre son utilisation en pratique clinique.
Thème proposé à 2 étudiants
2) SEP et Vieillissement :
Les progrès de la prise en charge médicale des patients présentant une Sclérose en Plaques (SEP) ont permis à ces patients d’avancer en âge. Toutefois, les tests évaluant leurs capacités cognitives sont généralement normés pour une population jeune.
L’objectif de ce travail d’études pour l’année 2017-18 sera de compléter le recueil de données contrôles à une batterie cognitive pour des personnes âgées de 50 à 75 ans dans le but d’établir une normalisation pour cette batterie et de pouvoir ainsi permettre son utilisation en pratique clinique auprès de patients souffrant d’une SEP.
Thème proposé à 2 étudiants
3) Evaluation des capacités de mémoire de travail :
Depuis cinq ans, en collaboration avec Yves Martin (Neuropsychologue, Centre l’Espoir), nous avons développé une version informatisée du paradigme de Brown Peterson. Ce paradigme permet d’évaluer les capacités de mémoire de travail des patients cérébrolésés.
Pour cette année universitaire (2017-18), il est nécessaire de poursuivre le travail de normalisation de cette épreuve. Les performances de 193 participants contrôles ont déjà été acquises. Il est à présent nécessaire de confirmer les premiers résultats obtenus dans le but de créer un outil clinique pouvant être utilisé en pratique clinique. Pour cela, il sera demandé de poursuivre le recueil de données auprès de participants contrôles. Ce thème de recherche est associé à un stage recherche de 60 heures au centre L’Espoir.
Thème proposé à 2 étudiants
- Thèmes de TER – Etudiants en 1ière année de Master
1) Intérêt des corrélations anatomo-cliniques chez les patients présentant une pathologie dégénérative :
La prise en charge des patients adressés en consultation mémoire se compose de plusieurs examens dont le bilan neuropsychologique et l’imagerie médicale. Il est proposé pour ce thème de mémoire d’établir des corrélations anatomo-clinique entre les performances obtenues au bilan neuropsychologique et à la scintigraphie cérébrale pour une cohorte de 30 patients adressés en consultation mémoire. L’objectif sera d’établir des corrélations entre des hypo-débits sanguins cérébraux et des performances déficitaires aux épreuves neuropsychologiques.
Thème proposé à 2 étudiants
2) Répartition des capacités d’attention visuelle en cas d’atteinte du champ visuel :
Les relations entre les capacités d’attention visuelle et le champ visuel nécessitent d’être mieux définies dans le but de pouvoir développer des procédures de remédiation chez les patients cérébrolésés. L’appréhension des relations attention visuelle – champ visuel sera menée à l’aide de deux études utilisant des dispositifs expérimentaux différents.
La première étude utilisant le dispositif : UFOV a été proposé à 140 participants présentant une atteinte du champ visuel avec ou sans trouble cognitif, le but de l’étude sera de définir des profils de performances attentionnels spécifiques ou non à chaque atteinte du champ visuel.
La seconde étude utilise l’épreuve du Test des Cloches, classiquement employé à la recherche d’une négligence visuelle. Il est dans le cadre de cette étude proposée d’élaborer une nouvelle procédure d’analyse des données se basant sur une démarche dynamique de la réalisation de cette épreuve. Les données de patients cérébrolésés et de sujets contrôles seront utilisées pour définir au mieux cette procédure d’analyse des données.
Thème proposé à 3 étudiants
3) Mémoire sémantique : Intérêt d’une procédure rapide d’évaluation.
Il existe encore peu de procédure rapide pour évaluer la mémoire sémantique. Depuis quelques années, nous avons développé un test rapide : DemensIA et recueilli des données après de sujets contrôles et de patients adressés en consultation mémoire. L’objectif de ce mémoire est de conduire les analyses des données recueillies pour permettre de déterminer si cet outil est valide et si alors établir des normes et/ou des profils contrôles.
Thème proposé à 2 étudiants
♦ Encadrement de thèse ♦
Guilbert Alma (2013-2016) : Prise en charge non-médicamenteuse des troubles attentionnels des patients cérébrolésés : apport de la pratique musicale
Nizzi Marie-Christine (2013-) : Le soi vécu en première et en troisième personne par les patients et leur entourage dans plusieurs types de démences neuro-dégénératives
MANOLI Romina (2016 -) : Évaluation des facteurs cognitifs et psychologiques prédictifs du retour en formation de patients cérébrolésés
♦ liens utiles en relation avec la neuropsychologie ♦
♦ Matériel de test ♦
1) Adaptation française du Stroop Victoria – f SV : Manuel et Fichier de correction en lien avec les articles suivants :
Moroni, C. & Bayard, S. (2009). Processus d’inhibition : Quelle est leur évolution après 50 ans ? Psychologie et Neuropsychiatrie du vieillissement, 2, 121-9.
Bayard, S., Erkes, J., Moroni,C. & les Membres du Collège des Psychologues spécialisés en Neuropsychologie du Languedoc-Roussillon (2011). Victoria Stroop Test: Normative data in a sample group of older people and the study of their clinical applications in the assessment of inhibition in Alzheimer’s disease. Archives of Neuropsychology, 26(7), 653-61.
2) Evaluation des praxies gestuelles : Feuille réponse et gestes sans signification en lien avec l’article suivant :
Mahieux, F., Fabre, C., Galbrun, E., Dubrulle, A. & Moroni, C. et le groupe de réflexion sur les praxies du CMRR Ile de France-Sud (2009). Validation d’une batterie brève d’évaluation des praxies gestuelles pour Consultation Mémoire. Evaluation chez 419 témoins, 127 MCI et 320 patients souffrant d’une démence. Revue Neurologique, 165, 560-67.
3) Test des Faux Pas : Consignes, Test version patient, Test support psychologue, Cotation, Données contrôles en lien avec la communication suivante :
Delbeuck, X. Boutantin, J., Leroy, A., Pollet, M., Lebert, F., Pasquier, F., & Moroni, C. (2011). Utilité clinique du test des Faux Pas pour le diagnostic de démence fronto-temporale. Intervention dans le cadre des Journées d’Hiver de la Société de Neuropsychologie de Langue Française, Paris, 2 décembre 2011 [communication écrite].
4) Fluence d’action : Consignes et Fichier de correction (automatic calculation file) en lien avec l’article suivant :
Delbeuck, X., Debachy, B., Pasquier, F. & Moroni, C. (2013). Action and noun fluence testing to distinguish between Alzheimer’s disease and dementia with Lewy bodies. Journal of Clinical and Experimental Neuropsychology. DOI:10.1080/13803395.2013.763907
5) Test d’écoute dichotique (TED) : Matériel et feuille de réponse
6) Version Française du Hayling Test : Manuel et Fichier de correction en lien avec les articles suivant :
Bayard, S., Gély-Nargeot M-C, Raffard, S., Guerdoux-Ninot, E., Kamara, E., Gros-Balthazard, F., Jacus J-P & Moroni C., The Collège des Psychologues Cliniciens spécialisés en Neuropsychologie du Languedoc Roussillon (CPCN-Languedoc Roussillon) (accepted).French version of the Hayling Sentence Completion Test, Part I : Normative date and guidelines for error scoring. Archives of Neuropsychology.
Bayard,S., Moroni, C., Gély-Nargeot, M-C, Rossignol-Arifi,A., Kamara, E. & RaffardS. (Accepted). French version of the Hayling Sentence Clompletion Test, Part II : Clinical utility in schizophrenia and Parkinson’s disease. Archives of Neuropsychology
♦ Publication ♦
Description :
L’évaluation neuropsychologique repose sur un ensemble de connaissances théoriques couplé à une méthodologie spécifique. Cet ouvrage rappelle les principes méthodologiques fondamentaux de la démarche du bilan neuropsychologique à visée diagnostique et propose un ensemble de 20 cas cliniques permettant aux futurs professionnels de se familiariser avec les savoirs-faire du psychologue spécialisé en neuropsychologie. D’où l’intérêt de cet ouvrage, véritable guide pratique qui fournit des illustrations concrètes avec des cas cliniques dans différents domaines d’application de la neuropsychologie.
Les Auteurs :
Christine MORONI : Professeur en neuropsychologie à l’Université Lille 3, elle est aussi psychologue spécialisée en neuropsychologie au au CHRU Salengro à Lille
Pauline NARME : Maître de conférences en neuropsychologie à l’Université Paris-Descartes
Editeur : Dunod (11 mai 2016)
Collection : Psycho Sup
Langue : Français
ISBN-10: 2100740237
ISBN-13: 978-2100740239
♦ Publications ♦
60 Entrées « ‹ 2 de 2
› »
2010
|
| 51. | Veronique, Le Guern; C, Belin; C, Henegar; Christine, Moroni; Didier, Maillet; C, Lacau; Louis, Dumas Jean; N, Vigneron; L, Guillevin Cognitive function and 99mTc-ECD brain SPECT are significantly correlated in patients with primary Sjögren syndrome: a case–control study Article de journal Dans: Ann Rheum Dis, 69 (01), p. 132–137, 2010, ISSN: , 1468-2060. Résumé | Liens | BibTeX @article{veronique_cognitive_2010,
title = {Cognitive function and 99mTc-ECD brain SPECT are significantly correlated in patients with primary Sjögren syndrome: a case–control study},
author = {Le Guern Veronique and Belin C and Henegar C and Moroni Christine and Maillet Didier and Lacau C and Dumas Jean Louis and Vigneron N and Guillevin L},
url = {http://ard.bmj.com/content/69/01/132},
doi = {10.1136/ard.2008.090811},
issn = {, 1468-2060},
year = {2010},
date = {2010-01-01},
urldate = {2015-03-26},
journal = {Ann Rheum Dis},
volume = {69},
number = {01},
pages = {132--137},
abstract = {Objectives: To assess subclinical central nervous system (CNS) involvement in primary Sjögren syndrome (pSS), by comparing standard brain MRI, in-depth neuropsychological testing and 99mTc-ECD brain single-photon emission computed tomography (SPECT) of patients with pSS with matched controls. Methods: 10 women (textless55 years old), with pSS defined using European–American criteria, presence of anti-SSA and/or anti-SSB antibodies and no history of neurological involvement were prospectively investigated, and compared with 10 age- and sex-matched controls. All subjects underwent, within 1 month, brain MRI, neuropsychological testing, including overall evaluation and focal cognitive function assessment, and 99mTc-ECD brain SPECT. Results: 99mTc-ECD brain SPECT abnormalities were significantly more common in patients with pSS (10/10) than controls (2/10; ptextless0.05). Cognitive dysfunctions, mainly expressed as executive and visuospatial disorders, were also significantly more common in patients with pSS (8/10) than controls (0/10; ptextless0.01). Notably, between-group comparisons enabled a significant correlation to be established between neuropsychological assessment and 99mTc-ECD brain SPECT abnormalities in patients with pSS (rs = 0.49, ptextless0.01). MRI abnormalities in patients and controls did not differ significantly. Conclusions: Neuropsychological testing and 99mTc-ECD brain SPECT seem to be the most sensitive tools to detect subclinical CNS dysfunction in pSS. The strong correlation between cortical hypoperfusion in 99mTc-ECD brain SPECT and cognitive dysfunction suggests an organic aetiology of CNS dysfunction in pSS. These data should be confirmed in a larger study.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Objectives: To assess subclinical central nervous system (CNS) involvement in primary Sjögren syndrome (pSS), by comparing standard brain MRI, in-depth neuropsychological testing and 99mTc-ECD brain single-photon emission computed tomography (SPECT) of patients with pSS with matched controls. Methods: 10 women (textless55 years old), with pSS defined using European–American criteria, presence of anti-SSA and/or anti-SSB antibodies and no history of neurological involvement were prospectively investigated, and compared with 10 age- and sex-matched controls. All subjects underwent, within 1 month, brain MRI, neuropsychological testing, including overall evaluation and focal cognitive function assessment, and 99mTc-ECD brain SPECT. Results: 99mTc-ECD brain SPECT abnormalities were significantly more common in patients with pSS (10/10) than controls (2/10; ptextless0.05). Cognitive dysfunctions, mainly expressed as executive and visuospatial disorders, were also significantly more common in patients with pSS (8/10) than controls (0/10; ptextless0.01). Notably, between-group comparisons enabled a significant correlation to be established between neuropsychological assessment and 99mTc-ECD brain SPECT abnormalities in patients with pSS (rs = 0.49, ptextless0.01). MRI abnormalities in patients and controls did not differ significantly. Conclusions: Neuropsychological testing and 99mTc-ECD brain SPECT seem to be the most sensitive tools to detect subclinical CNS dysfunction in pSS. The strong correlation between cortical hypoperfusion in 99mTc-ECD brain SPECT and cognitive dysfunction suggests an organic aetiology of CNS dysfunction in pSS. These data should be confirmed in a larger study. |
2009
|
| 52. | Mahieux-Laurent, F; Fabre, C; Galbrun, E; Dubrulle, A; Moroni, C [Validation of a brief screening scale evaluating praxic abilities for use in memory clinics. Evaluation in 419 controls, 127 mild cognitive impairment and 320 demented patients]. Article de journal Dans: Revue neurologique, 165 (6-7), p. 560–7, 2009, ISSN: 0035-3787. Résumé | Liens | BibTeX @article{mahieux-laurent_[validation_2009,
title = {[Validation of a brief screening scale evaluating praxic abilities for use in memory clinics. Evaluation in 419 controls, 127 mild cognitive impairment and 320 demented patients].},
author = {F Mahieux-Laurent and C Fabre and E Galbrun and A Dubrulle and C Moroni},
url = {http://www.ncbi.nlm.nih.gov/pubmed/19150097},
doi = {10.1016/j.neurol.2008.11.016},
issn = {0035-3787},
year = {2009},
date = {2009-01-01},
journal = {Revue neurologique},
volume = {165},
number = {6-7},
pages = {560--7},
abstract = {INTRODUCTION: The aim of this study was to build a brief clinical scale evaluating praxic abilities of the upper limbs for use in memory clinics and to produce norms. PATIENTS AND METHODS: The scale includes three subtests: symbolic gestures (five gestures), pantomimes (five gestures) and imitation of meaningless gestures (eight gestures). Data were collected in a sample of 419 normal subjects. Sensitivity and specificity were established from their comparison to data collected from 320 demented patients. A group of 127 patients with mild cognitive impairment was also studied. RESULTS: Cut-off scores were proposed based on the fifth percentile observed in three classes of age and three levels of education. The specificity was high. Sensitivity was higher for imitation of meaningless gestures than for pantomimes and the least for symbolic gestures. The group of patients with mild cognitive impairment was half-way between demented patients and normal subjects. CONCLUSION: The proposed scale meets its initial aims of brevity and high specificity. It can easily be used in memory clinics and identifies apraxia in dementia patients. It therefore usefully contributes to clinical diagnosis.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
INTRODUCTION: The aim of this study was to build a brief clinical scale evaluating praxic abilities of the upper limbs for use in memory clinics and to produce norms. PATIENTS AND METHODS: The scale includes three subtests: symbolic gestures (five gestures), pantomimes (five gestures) and imitation of meaningless gestures (eight gestures). Data were collected in a sample of 419 normal subjects. Sensitivity and specificity were established from their comparison to data collected from 320 demented patients. A group of 127 patients with mild cognitive impairment was also studied. RESULTS: Cut-off scores were proposed based on the fifth percentile observed in three classes of age and three levels of education. The specificity was high. Sensitivity was higher for imitation of meaningless gestures than for pantomimes and the least for symbolic gestures. The group of patients with mild cognitive impairment was half-way between demented patients and normal subjects. CONCLUSION: The proposed scale meets its initial aims of brevity and high specificity. It can easily be used in memory clinics and identifies apraxia in dementia patients. It therefore usefully contributes to clinical diagnosis. |
| 53. | Maillet, Didier; Moroni, Christine; Belin, Catherine L’atrophie corticale postérieure Article de journal Dans: Psychologie et Neuropsychiatrie du vieillissement, 3 , p. 193–203, 2009. BibTeX @article{maillet_latrophie_2009,
title = {L’atrophie corticale postérieure},
author = {Didier Maillet and Christine Moroni and Catherine Belin},
year = {2009},
date = {2009-01-01},
journal = {Psychologie et Neuropsychiatrie du vieillissement},
volume = {3},
pages = {193--203},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 54. | Hommet, Caroline; Beauchet, Olivier; Moroni, Christine; Mondon, Karl; Perrier, Danièle; Berrut, Gilles; Constans, Thierry [Cerebral lateralization and hemispheric interaction in aging: what about dichotic listening?]. Article de journal Dans: Psychologie & neuropsychiatrie du vieillissement, 7 (1), p. 65–72, 2009, ISSN: 1760-1703. Résumé | Liens | BibTeX @article{hommet_[cerebral_2009,
title = {[Cerebral lateralization and hemispheric interaction in aging: what about dichotic listening?].},
author = {Caroline Hommet and Olivier Beauchet and Christine Moroni and Karl Mondon and Danièle Perrier and Gilles Berrut and Thierry Constans},
url = {http://www.ncbi.nlm.nih.gov/pubmed/19251573},
doi = {10.1684/pnv.2009.0158},
issn = {1760-1703},
year = {2009},
date = {2009-01-01},
journal = {Psychologie & neuropsychiatrie du vieillissement},
volume = {7},
number = {1},
pages = {65--72},
abstract = {Dichotic listening is the most frequent behavioral test used to assess hemispheric lateralization. The subjects simultaneously receive competing information signals in each ear and the attention resources are mobilized. Dichotic listening may be viewed as a dual-task procedure. In fact, executive functions and attention, which are involved, may be modified in elderly. The aim of this paper is to define the role of dichotic listening for the study of hemispheric interactions in the elderly, according to compensation/reorganization processes in normal and pathological aging.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dichotic listening is the most frequent behavioral test used to assess hemispheric lateralization. The subjects simultaneously receive competing information signals in each ear and the attention resources are mobilized. Dichotic listening may be viewed as a dual-task procedure. In fact, executive functions and attention, which are involved, may be modified in elderly. The aim of this paper is to define the role of dichotic listening for the study of hemispheric interactions in the elderly, according to compensation/reorganization processes in normal and pathological aging. |
2008
|
| 55. | Sabbah, Nathanael; Gelbert, Françoise; Nioche, Christophe; Moroni, Christine; Goasdoué, Pascal; Belin, Catherine; Sabbah, Patrick Modern concepts of normal language and impairments Article de journal Dans: Clinical Imaging, 32 (6), p. 425–430, 2008, ISSN: 0899-7071. Résumé | Liens | BibTeX @article{sabbah_modern_2008,
title = {Modern concepts of normal language and impairments},
author = {Nathanael Sabbah and Françoise Gelbert and Christophe Nioche and Christine Moroni and Pascal Goasdoué and Catherine Belin and Patrick Sabbah},
url = {http://www.sciencedirect.com/science/article/pii/S0899707108000909},
doi = {10.1016/j.clinimag.2008.02.029},
issn = {0899-7071},
year = {2008},
date = {2008-01-01},
urldate = {2015-03-26},
journal = {Clinical Imaging},
volume = {32},
number = {6},
pages = {425--430},
abstract = {Language is a primary factor in comprehending the functional organization of the brain. Starting with the static anatomoclinical model, followed by the limited aphasiological model, functional imaging techniques have allowed a more dynamic approach that adds complexity to the study of the interaction between brain and language, and bespeak the influence of parameters such as age, sex, motivation, and stress.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Language is a primary factor in comprehending the functional organization of the brain. Starting with the static anatomoclinical model, followed by the limited aphasiological model, functional imaging techniques have allowed a more dynamic approach that adds complexity to the study of the interaction between brain and language, and bespeak the influence of parameters such as age, sex, motivation, and stress. |
2007
|
| 56. | Bayard, S; Bonte, Adnet C; Nibbio, A; Moroni, C Brève communication Exagération de symptômes mnésiques hors contexte médicolégal chez un patient atteint de sclérose en plaques Article de journal Dans: 100 , p. 730–733, 2007. BibTeX @article{bayard_breve_2007,
title = {Brève communication Exagération de symptômes mnésiques hors contexte médicolégal chez un patient atteint de sclérose en plaques},
author = {S Bayard and Adnet C Bonte and A Nibbio and C Moroni},
year = {2007},
date = {2007-01-01},
volume = {100},
pages = {730--733},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2004
|
| 57. | Sylvain, Clément; Christine, Moroni; Séverine, Samson Modularity in Sensory Auditory Memory Article de journal Dans: Polskie Forum Psychologiczne, 2004. BibTeX @article{sylvain_modularity_2004,
title = {Modularity in Sensory Auditory Memory},
author = {Clément Sylvain and Moroni Christine and Samson Séverine},
year = {2004},
date = {2004-01-01},
journal = {Polskie Forum Psychologiczne},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 58. | Bartolomeo, Paolo; Urbanski, Marika; Chokron, Sylvie; Chainay, Hanna; Moroni, Christine; Siéroff, Eric; Belin, Catherine; Halligan, Peter Neglected attention in apparent spatial compression Article de journal Dans: Neuropsychologia, 42 (1), p. 49–61, 2004, ISSN: 00283932. Liens | BibTeX @article{bartolomeo_neglected_2004,
title = {Neglected attention in apparent spatial compression},
author = {Paolo Bartolomeo and Marika Urbanski and Sylvie Chokron and Hanna Chainay and Christine Moroni and Eric Siéroff and Catherine Belin and Peter Halligan},
url = {http://linkinghub.elsevier.com/retrieve/pii/S0028393203001465},
doi = {10.1016/S0028-3932(03)00146-5},
issn = {00283932},
year = {2004},
date = {2004-01-01},
journal = {Neuropsychologia},
volume = {42},
number = {1},
pages = {49--61},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 59. | Moroni, C; Belin, C; Haguenau, M; Salama, J Clinical callosum syndrome in a case of multiple sclerosis. Article de journal Dans: European journal of neurology : the official journal of the European Federation of Neurological Societies, 11 (3), p. 209–12, 2004, ISSN: 1351-5101. Résumé | Liens | BibTeX @article{moroni_clinical_2004,
title = {Clinical callosum syndrome in a case of multiple sclerosis.},
author = {C Moroni and C Belin and M Haguenau and J Salama},
url = {http://www.ncbi.nlm.nih.gov/pubmed/15009167},
issn = {1351-5101},
year = {2004},
date = {2004-01-01},
journal = {European journal of neurology : the official journal of the European Federation of Neurological Societies},
volume = {11},
number = {3},
pages = {209--12},
abstract = {This case report confirms that a clinical callosal disconnection could be observed in multiple sclerosis. Moreover, this case describes a new kind of strange manual behavior related to callosal disconnection. This behavior could neither be considered as a diagonistic dyspraxia nor as an alien hand, but they evoke rather a conflict of intentions.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
This case report confirms that a clinical callosal disconnection could be observed in multiple sclerosis. Moreover, this case describes a new kind of strange manual behavior related to callosal disconnection. This behavior could neither be considered as a diagonistic dyspraxia nor as an alien hand, but they evoke rather a conflict of intentions. |
2000
|
| 60. | Lorenzi, Christian; Wable, Jocelyne; Moroni, Christine; Derobert, Christophe; Frachet, Bruno; Belin, Catherine Auditory temporal envelope processing in a patient with left-hemisphere damage Article de journal Dans: Neurocase: The Neural Basis of Cognition, 6 (3), p. 231–244, 2000, ISSN: 1355-4794. Résumé | Liens | BibTeX @article{lorenzi_auditory_2000,
title = {Auditory temporal envelope processing in a patient with left-hemisphere damage},
author = {Christian Lorenzi and Jocelyne Wable and Christine Moroni and Christophe Derobert and Bruno Frachet and Catherine Belin},
url = {http://dx.doi.org/10.1080/13554790008402773},
doi = {10.1080/13554790008402773},
issn = {1355-4794},
year = {2000},
date = {2000-05-01},
urldate = {2016-05-03},
journal = {Neurocase: The Neural Basis of Cognition},
volume = {6},
number = {3},
pages = {231--244},
abstract = {Auditory temporal envelope processing was investigated in a patient showing a mild speech identification impairment following left-hemisphere damage. Three tasks evaluated the patient's ability to: (1) detect a sinusoidal amplitude modulation (SAM) applied to a white noise, as a function of modulation rate (i.e. her ‘temporal modulation transfer function’ or TMTF); (2) discriminate between two white noises amplitude modulated by time-reversed temporally asymmetric envelopes; and (3) identify white noises amplitude modulated by the temporal envelope of speech stimuli. Measurements of intensity discrimination thresholds were performed as a control task. Compared to normal data, the results obtained with the brain-damaged patient showed: (1) increased thresholds for the detection of SAM; (2) increased thresholds for the discrimination of temporal asymmetry; and (3) a deficit in the identification of speechenvelope noise stimuli. In contrast, intensity discrimination thresholds were within the normal range. Taken together, the results indicate a general impairment in auditory temporal acuity, which is now specified as a deficit in the coding of envelope rate and shape, and a deficit in the ability to use temporal envelope cues in speech processing. These results support the hypothesis that left-hemisphere damage is associated with an impairment in time analysis, which may cause, in turn, speech intelligibility disorders.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Auditory temporal envelope processing was investigated in a patient showing a mild speech identification impairment following left-hemisphere damage. Three tasks evaluated the patient's ability to: (1) detect a sinusoidal amplitude modulation (SAM) applied to a white noise, as a function of modulation rate (i.e. her ‘temporal modulation transfer function’ or TMTF); (2) discriminate between two white noises amplitude modulated by time-reversed temporally asymmetric envelopes; and (3) identify white noises amplitude modulated by the temporal envelope of speech stimuli. Measurements of intensity discrimination thresholds were performed as a control task. Compared to normal data, the results obtained with the brain-damaged patient showed: (1) increased thresholds for the detection of SAM; (2) increased thresholds for the discrimination of temporal asymmetry; and (3) a deficit in the identification of speechenvelope noise stimuli. In contrast, intensity discrimination thresholds were within the normal range. Taken together, the results indicate a general impairment in auditory temporal acuity, which is now specified as a deficit in the coding of envelope rate and shape, and a deficit in the ability to use temporal envelope cues in speech processing. These results support the hypothesis that left-hemisphere damage is associated with an impairment in time analysis, which may cause, in turn, speech intelligibility disorders. |
60 Entrées « ‹ 2 de 2
› » Mise à jour le 2017-08-29 à 12:05:06
