Rôle du lobe temporal dans la mémoire musicale à travers l’analyse des pathologies cérébrales Bénéfices de la musique dans la prise en charge des démences: Thérapies non médicamenteuses Emotions non verbales (musicales, vocales, corporelles, faciales): intégration multimodale et analyse du décours temporel.
La musique semble douée du pouvoir de moduler la cognition et de communiquer des émotions sans médiation verbale, influençant ainsi l’architecture fonctionnelle et anatomique du cerveau. A partir d’une approche transdisciplinaire qui associe la psychologie cognitive et sociale à l’imagerie cérébrale, la musique est utilisée comme outil de stimulation cognitive et sensorielle afin d’exploiter les propriétés mnémoniques et communicatives d’un texte porté par la voix chantée. La musique permettra aussi de renforcer l’intégration multi-‐modale et d’améliorer la prise en charge et le bien-‐être des patients présentant des déficits mnésiques (maladie d’Alzheimer, épilepsie) ou de la communication (dysphasie, surdité). Comprendre la plasticité cérébrale musicalement induite constitue un enjeu déterminant pour les neurosciences cliniques tout en ouvrant des perspectives thérapeutiques prometteuses et innovantes.
2018
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| 1. | Mathon, Bertrand; Samson, Séverine; Dupont, Sophie; Clémenceau, Stéphane Reply to the Letter to the Editor ``Selective Amygdalohippocampectomy for Mesial Temporal Sclerosis; Special Considerations in Genius Individuals'' Article de journal Forthcoming Dans: World Neurosurg, Forthcoming. BibTeX @article{Mathon2018,
title = {Reply to the Letter to the Editor ``Selective Amygdalohippocampectomy for Mesial Temporal Sclerosis; Special Considerations in Genius Individuals''},
author = {Bertrand Mathon and Séverine Samson and Sophie Dupont and Stéphane Clémenceau},
year = {2018},
date = {2018-01-25},
journal = {World Neurosurg},
keywords = {},
pubstate = {forthcoming},
tppubtype = {article}
}
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2017
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| 2. | Cabrera, Stéphane Solano; Lehéricy, ; Masson, Véronique; Samson, Séverine; Dupont, Sophie Adapting a memory fMRI research protocol in clinical routine: feasibility and results Article de journal Forthcoming Dans: Epilepsy and Behavior, Forthcoming. BibTeX @article{Cabrera2017,
title = {Adapting a memory fMRI research protocol in clinical routine: feasibility and results},
author = {Stéphane Solano Cabrera and Lehéricy and Véronique Masson and Séverine Samson and Sophie Dupont},
year = {2017},
date = {2017-12-30},
journal = {Epilepsy and Behavior},
keywords = {},
pubstate = {forthcoming},
tppubtype = {article}
}
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| 3. | Mathon, B; Bielle, F; Samson, S; Plaisant, O; Dupont, S; Bertrand, A; Miles, R; Nguyen-Michel, V -H; Lambrecq, V; Calderon-Garcidueñas, A L; Duyckaerts, C; Carpentier, A; Baulac, M; Cornu, P; Adam, C; Clemenceau, S; Navarro, V Predictive factors of long-term outcomes of surgery for mesial temporal lobe epilepsy associated with hippocampal sclerosis - Mathon - 2017 - Epilepsia - Wiley Online Library Article de journal Dans: Epilepsia, p. 1-13, 2017. Liens | BibTeX @article{Mathon2017,
title = {Predictive factors of long-term outcomes of surgery for mesial temporal lobe epilepsy associated with hippocampal sclerosis - Mathon - 2017 - Epilepsia - Wiley Online Library},
author = {B. Mathon and F. Bielle and S. Samson and O. Plaisant and S. Dupont and A. Bertrand and R. Miles and V.-H. Nguyen-Michel and V. Lambrecq and A. L. Calderon-Garcidueñas and C. Duyckaerts and A. Carpentier and M. Baulac and P. Cornu and C. Adam and S. Clemenceau and V. Navarro},
url = {http://onlinelibrary.wiley.com/doi/10.1111/epi.13831/full},
doi = {DOI: 10.1111/epi.13831},
year = {2017},
date = {2017-06-28},
urldate = {2017-07-20},
journal = {Epilepsia},
pages = {1-13},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 4. | Cason, Nia; Schiaratura, Loris; Samson, Séverine Synchronisation to music as a tool for enhancing non-verbal communication in neuropsychology. Book Chapter Dans: by: Lesaffre, Edited Micheline; Maes, Pieter-Jan; to Interaction., Marc Leman The Routledge Companion Embodied Music : (Ed.): 2017, ISBN: 9781138657403 . Résumé | Liens | BibTeX @inbook{Cason2017,
title = {Synchronisation to music as a tool for enhancing non-verbal communication in neuropsychology. },
author = {Nia Cason and Loris Schiaratura and Séverine Samson},
editor = { Edited by: Micheline Lesaffre and Pieter-Jan Maes and Marc Leman : The Routledge Companion to Embodied Music Interaction.},
url = {https://www.routledgehandbooks.com/doi/10.4324/9781315621364.ch33},
doi = {10.4324/9781315621364.ch33 },
isbn = {9781138657403 },
year = {2017},
date = {2017-04-01},
abstract = {Almost all social interactions—both verbal and non-verbal—are said to rely on rhythmic behaviors (Bispham, 2006). “Interpersonal coordination” can be described as the spatial or temporal coordination of communicative behaviors between interacting individuals. Of specific interest in this chapter is the synchronization of non-verbal behaviors. We will argue that synchronization to music can enhance interpersonal coordination, and thus can improve social functioning and non-verbal communication skills. This is highly relevant for patients with communication difficulties, such as patients with Alzheimer’s disease (AD) and dementia.},
keywords = {},
pubstate = {published},
tppubtype = {inbook}
}
Almost all social interactions—both verbal and non-verbal—are said to rely on rhythmic behaviors (Bispham, 2006). “Interpersonal coordination” can be described as the spatial or temporal coordination of communicative behaviors between interacting individuals. Of specific interest in this chapter is the synchronization of non-verbal behaviors. We will argue that synchronization to music can enhance interpersonal coordination, and thus can improve social functioning and non-verbal communication skills. This is highly relevant for patients with communication difficulties, such as patients with Alzheimer’s disease (AD) and dementia. |
| 5. | Omigie, D; Dellacherie, D; Samson, S Effects of learning processes on dissonance judgments, special issue Cognition of Early Polyphony: Bringing Together Humanities and Sciences Article de journal Dans: Journal of Interdisciplinary Music Studies, 8 (142), p. 11-29, 2017. Liens | BibTeX @article{Omigie2017,
title = { Effects of learning processes on dissonance judgments, special issue Cognition of Early Polyphony: Bringing Together Humanities and Sciences},
author = {D. Omigie and D. Dellacherie and S. Samson},
url = {http://musicstudies.org/wp-content/uploads/2017/03/Omigie_JIMS_16081201.pdf},
doi = {doi: 10.4407 /jims.2016 . 12 .001},
year = {2017},
date = {2017-03-15},
urldate = {2017-07-17},
journal = {Journal of Interdisciplinary Music Studies},
volume = {8},
number = {142},
pages = {11-29},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 6. | Ambert-Dahan, Emmanuelle; Giraud, Anne-Lise; Mecheri, Halima; Sterkers, Olivier; Mosnier, Isabelle; Samson, Séverine Emotional recognition of dynamic facial expressions before and after cochlear implantation in adults with progressive deafness Article de journal Dans: Hearing research, 354 , p. 64–72, 2017, ISSN: 1878-5891. Résumé | Liens | BibTeX @article{Ambert-Dahan2017,
title = {Emotional recognition of dynamic facial expressions before and after cochlear implantation in adults with progressive deafness},
author = {Emmanuelle Ambert-Dahan and Anne-Lise Giraud and Halima Mecheri and Olivier Sterkers and Isabelle Mosnier and Séverine Samson},
doi = {10.1016/j.heares.2017.08.007},
issn = {1878-5891},
year = {2017},
date = {2017-01-01},
journal = {Hearing research},
volume = {354},
pages = {64--72},
abstract = {Visual processing has been extensively explored in deaf subjects in the context of verbal communication, through the assessment of speech reading and sign language abilities. However, little is known about visual emotional processing in adult progressive deafness, and after cochlear implantation. The goal of our study was thus to assess the influence of acquired post-lingual progressive deafness on the recognition of dynamic facial emotions that were selected to express canonical fear, happiness, sadness, and anger. A total of 23 adults with post-lingual deafness separated into two groups; those assessed either before (n~=~10) and those assessed after (n~=~13) cochlear implantation (CI); and 13 normal hearing (NH) individuals participated in the current study. Participants were asked to rate the expression of the four cardinal emotions, and to evaluate both their emotional valence (unpleasant-pleasant) and arousal potential (relaxing-stimulating). We found that patients with deafness were impaired in the recognition of sad faces, and that patients equipped with a CI were additionally impaired in the recognition of happiness and fear (but not anger). Relative to controls, all patients with deafness showed a deficit in perceiving arousal expressed in faces, while valence ratings remained unaffected. The current results show for the first time that acquired and progressive deafness is associated with a reduction of emotional sensitivity to visual stimuli. This negative impact of progressive deafness on the perception of dynamic facial cues for emotion recognition contrasts with the proficiency of deaf subjects with and without CIs in processing visual speech cues (Rouger et~al., 2007; Strelnikov et~al., 2009; Lazard and Giraud, 2017). Altogether these results suggest there to be a trade-off between the processing of linguistic and non-linguistic visual stimuli.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Visual processing has been extensively explored in deaf subjects in the context of verbal communication, through the assessment of speech reading and sign language abilities. However, little is known about visual emotional processing in adult progressive deafness, and after cochlear implantation. The goal of our study was thus to assess the influence of acquired post-lingual progressive deafness on the recognition of dynamic facial emotions that were selected to express canonical fear, happiness, sadness, and anger. A total of 23 adults with post-lingual deafness separated into two groups; those assessed either before (n~=~10) and those assessed after (n~=~13) cochlear implantation (CI); and 13 normal hearing (NH) individuals participated in the current study. Participants were asked to rate the expression of the four cardinal emotions, and to evaluate both their emotional valence (unpleasant-pleasant) and arousal potential (relaxing-stimulating). We found that patients with deafness were impaired in the recognition of sad faces, and that patients equipped with a CI were additionally impaired in the recognition of happiness and fear (but not anger). Relative to controls, all patients with deafness showed a deficit in perceiving arousal expressed in faces, while valence ratings remained unaffected. The current results show for the first time that acquired and progressive deafness is associated with a reduction of emotional sensitivity to visual stimuli. This negative impact of progressive deafness on the perception of dynamic facial cues for emotion recognition contrasts with the proficiency of deaf subjects with and without CIs in processing visual speech cues (Rouger et~al., 2007; Strelnikov et~al., 2009; Lazard and Giraud, 2017). Altogether these results suggest there to be a trade-off between the processing of linguistic and non-linguistic visual stimuli. |
| 7. | Paquette, Sébastien; Fournier, Philippe; Dupont, Sophie; de Edelenyi, Fabien Szabo; Galan, Pilar; Samson, Séverine Risk of Tinnitus After Medial Temporal Lobe Surgery Article de journal Dans: JAMA neurology, 74 (11), p. 1376–1377, 2017, ISSN: 2168-6157. Liens | BibTeX @article{Paquette2017,
title = {Risk of Tinnitus After Medial Temporal Lobe Surgery},
author = {Sébastien Paquette and Philippe Fournier and Sophie Dupont and Fabien Szabo de Edelenyi and Pilar Galan and Séverine Samson},
doi = {10.1001/jamaneurol.2017.2718.},
issn = {2168-6157},
year = {2017},
date = {2017-01-01},
journal = {JAMA neurology},
volume = {74},
number = {11},
pages = {1376--1377},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2016
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| 8. | Dinkelacker, Vera; Xin, X; Samson, Severine; Baulac, Michel; Dupont, Sophie Interictal discharge correlates with global and frontal cognitive dysfunction in temporal lobe epilepsy in Epilepsy and Behavior (in Press) Article de journal Dans: Epilepsy and Behavior, 2016. BibTeX @article{dinkelacker_interictal_2016,
title = {Interictal discharge correlates with global and frontal cognitive dysfunction in temporal lobe epilepsy in Epilepsy and Behavior (in Press)},
author = {Vera Dinkelacker and X Xin and Severine Samson and Michel Baulac and Sophie Dupont},
year = {2016},
date = {2016-01-01},
journal = {Epilepsy and Behavior},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 9. | Baird, Amee; Samson, Séverine; Miller, Laurie; Chalmers, Kerry Does music training facilitate the mnemonic effect of song? An exploration of musicians and nonmusicians with and without Alzheimer's dementia Article de journal Dans: J Clin Exp Neuropsychol, p. 1–13, 2016, ISSN: 1744-411X. Résumé | Liens | BibTeX @article{baird_does_2016,
title = {Does music training facilitate the mnemonic effect of song? An exploration of musicians and nonmusicians with and without Alzheimer's dementia},
author = {Amee Baird and Séverine Samson and Laurie Miller and Kerry Chalmers},
doi = {10.1080/13803395.2016.1185093},
issn = {1744-411X},
year = {2016},
date = {2016-01-01},
journal = {J Clin Exp Neuropsychol},
pages = {1--13},
abstract = {INTRODUCTION: The efficacy of using sung words as a mnemonic device for verbal memory has been documented in persons with probable Alzheimer's dementia (AD), but it is not yet known whether this effect is related to music training. Given that music training can enhance cognitive functioning, we explored the effects of music training and modality (sung vs. spoken) on verbal memory in persons with and without AD. METHOD: We used a mixed factorial design to compare learning (5 trials), delayed recall (30-min and, 24-hour), and recognition of sung versus spoken information in 22 healthy elderly (15 musicians), and 11 people with AD (5 musicians). RESULTS: Musicians with AD showed better total learning (over 5 trials) of sung information than nonmusicians with AD. There were no significant differences in delayed recall and recognition accuracy (of either modality) between musicians with and without AD, suggesting that music training may facilitate memory function in AD. Analysis of individual performances showed that two of the five musicians with AD were able to recall some information on delayed recall, whereas the nonmusicians with AD recalled no information on delay. The only significant finding in regard to modality (sung vs. spoken) was that total learning was significantly worse for sung than spoken information for nonmusicians with AD. This may be due to the need to recode information presented in song into spoken recall, which may be more cognitively demanding for this group. CONCLUSIONS: This is the first study to demonstrate that music training modulates memory of sung and spoken information in AD. The mechanism underlying these results is unclear, but may be due to music training, higher cognitive abilities, or both. Our findings highlight the need for further research into the potentially protective effect of music training on cognitive abilities in our aging population.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
INTRODUCTION: The efficacy of using sung words as a mnemonic device for verbal memory has been documented in persons with probable Alzheimer's dementia (AD), but it is not yet known whether this effect is related to music training. Given that music training can enhance cognitive functioning, we explored the effects of music training and modality (sung vs. spoken) on verbal memory in persons with and without AD. METHOD: We used a mixed factorial design to compare learning (5 trials), delayed recall (30-min and, 24-hour), and recognition of sung versus spoken information in 22 healthy elderly (15 musicians), and 11 people with AD (5 musicians). RESULTS: Musicians with AD showed better total learning (over 5 trials) of sung information than nonmusicians with AD. There were no significant differences in delayed recall and recognition accuracy (of either modality) between musicians with and without AD, suggesting that music training may facilitate memory function in AD. Analysis of individual performances showed that two of the five musicians with AD were able to recall some information on delayed recall, whereas the nonmusicians with AD recalled no information on delay. The only significant finding in regard to modality (sung vs. spoken) was that total learning was significantly worse for sung than spoken information for nonmusicians with AD. This may be due to the need to recode information presented in song into spoken recall, which may be more cognitively demanding for this group. CONCLUSIONS: This is the first study to demonstrate that music training modulates memory of sung and spoken information in AD. The mechanism underlying these results is unclear, but may be due to music training, higher cognitive abilities, or both. Our findings highlight the need for further research into the potentially protective effect of music training on cognitive abilities in our aging population. |
| 10. | Alonso, Irene; Davachi, Lila; Valabrègue, Romain; Lambrecq, Virginie; Dupont, Sophie; Samson, Séverine Neural correlates of binding lyrics and melodies for the encoding of new songs Article de journal Dans: NeuroImage, 127 , p. 333–345, 2016, ISSN: 1053-8119. Résumé | Liens | BibTeX @article{alonso_neural_2016,
title = {Neural correlates of binding lyrics and melodies for the encoding of new songs},
author = {Irene Alonso and Lila Davachi and Romain Valabrègue and Virginie Lambrecq and Sophie Dupont and Séverine Samson},
url = {http://www.sciencedirect.com/science/article/pii/S1053811915011313},
doi = {10.1016/j.neuroimage.2015.12.018},
issn = {1053-8119},
year = {2016},
date = {2016-01-01},
urldate = {2016-01-27},
journal = {NeuroImage},
volume = {127},
pages = {333--345},
abstract = {Songs naturally bind lyrics and melody into a unified representation. Using a subsequent memory paradigm, we examined the neural processes associated with binding lyrics and melodies during song encoding. Participants were presented with songs in two conditions: a unified condition (melodies sung with lyrics), and a separate condition (melodies sung with the syllable “la”). In both cases, written lyrics were displayed and participants were instructed to memorize them by repeating them covertly or by generating mental images of the songs. We expected the unified condition to recruit the posterior superior temporal gyrus, known to be involved in perceptual integration of songs, as well as the left inferior frontal gyrus (IFG). Conversely, we hypothesized that the separate condition would engage a larger network including the hippocampus to bind lyrics and melodies of songs, and the basal ganglia and the cerebellum to ensure the correct sequence coupling of verbal and musical information in time. Binding lyrics and melodies in the unified condition revealed activation of the left IFG, bilateral middle temporal gyrus (MTG), and left motor cortex, suggesting a strong linguistic processing for this condition. Binding in the separate compared to the unified condition revealed greater activity in the right hippocampus as well as other areas including the left caudate, left cerebellum, and right IFG. This study provides novel evidence for the role of the right hippocampus in binding lyrics and melodies in songs. Results are discussed in light of studies of binding in the visual domain and highlight the role of regions involved in timing and synchronization such as the basal ganglia and the cerebellum.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Songs naturally bind lyrics and melody into a unified representation. Using a subsequent memory paradigm, we examined the neural processes associated with binding lyrics and melodies during song encoding. Participants were presented with songs in two conditions: a unified condition (melodies sung with lyrics), and a separate condition (melodies sung with the syllable “la”). In both cases, written lyrics were displayed and participants were instructed to memorize them by repeating them covertly or by generating mental images of the songs. We expected the unified condition to recruit the posterior superior temporal gyrus, known to be involved in perceptual integration of songs, as well as the left inferior frontal gyrus (IFG). Conversely, we hypothesized that the separate condition would engage a larger network including the hippocampus to bind lyrics and melodies of songs, and the basal ganglia and the cerebellum to ensure the correct sequence coupling of verbal and musical information in time. Binding lyrics and melodies in the unified condition revealed activation of the left IFG, bilateral middle temporal gyrus (MTG), and left motor cortex, suggesting a strong linguistic processing for this condition. Binding in the separate compared to the unified condition revealed greater activity in the right hippocampus as well as other areas including the left caudate, left cerebellum, and right IFG. This study provides novel evidence for the role of the right hippocampus in binding lyrics and melodies in songs. Results are discussed in light of studies of binding in the visual domain and highlight the role of regions involved in timing and synchronization such as the basal ganglia and the cerebellum. |
Dans le cadre de ces TER, les étudiants devront receuillir des données chez des volontaires sains durant la 1ère année de master avant d’envisager des applications en neuropsychologie en 2ème année de master auprès de populations cliniques présentant une lésion neurologique, un trouble développemental ou un déficit sensoriel (surdité acquise). Certains projets pourront être réalisés en collaboration avec les centres hospitaliers de Lille, de Reims ou de Paris.
